This study proposes a theoretical approach to the idea of a platform for research and education on the historical substance of regionalization in Romania, with reference to the case of the historical province of Moldova. Furthermore, to identify the consequences, reactions, weaknesses, opportunities afforded by administrative restructuring from a postregionalization demographic and socioeconomic viewpoint. An inter-disciplinary analysis -historical, demographic, economic -the traits of a Romanian society stemming from Moldova, the historical dynamics that underpin the modern Romanian state, will provide a picture of the current situation, focused mainly on its causes while trying to find explanations rooted in economic and social behaviours and attitudes which came to define and inform the subsequent development strategy of regionalization, allowing Moldova to play a central economic role in relation to other territories, similar to the role it played in the past two centuries, in the context of European integration strategies, in neighbouring parts of the continent (Republic of Moldova, Ukraine). The theoretical approach involves three components, expanding concentrically: 1) component of knowledge / research; 2) digital platform; 3) e-learning component. The research component seeks dynamic historical development of Moldova, from the time after the Union of the Romanian Principalities until today, focusing on specific regional elements. We will try to identify and analyze the specific features of Moldova, links with other areas of historical Moldavia, as the interaction between them and the Romanian public policy. Within the demographic component, we look at the historical population dynamics of Moldova, including various ethnic and religious communities, rural-urban ratios, social and professional structures. Another issue concerns the economic and comparative analysis in space and time, with respect to Moldova historical economic dynamics parameters -resources, infrastructure, industry, agriculture, trade, transport, etc. Both aspects will be analyzed in correlation with the impact of a permanent political factor, pursuing public policies promoted by the political regimes in their chronological sequence.UDC Classification: 94(4/9); DOI: http://dx