Results are presented from searches for the standard model Higgs boson in proton-proton collisions at root s = 7 and 8 TeV in the Compact Muon Solenoid experiment at the LHC, using data samples corresponding to integrated luminosities of up to 5.1 fb(-1) at 7 TeV and 5.3 fb(-1) at 8 TeV. The search is performed in five decay modes: gamma gamma, ZZ, W+W-, tau(+)tau(-), and b (b) over bar. An excess of events is observed above the expected background, with a local significance of 5.0 standard deviations, at a mass near 125 GeV, signalling the production of a new particle. The expected significance for a standard model Higgs boson of that mass is 5.8 standard deviations. The excess is most significant in the two decay modes with the best mass resolution, gamma gamma and ZZ; a fit to these signals gives a mass of 125.3 +/- 0.4(stat.) +/- 0.5(syst.) GeV. The decay to two photons indicates that the new particle is a boson with spin different from one. (C) 2012 CERN. Published by Elsevier B.V. All rights reserved

Recent results of the searches for Supersymmetry in final states with one or two leptons at CMS are presented. Many Supersymmetry scenarios, including the Constrained Minimal Supersymmetric extension of the Standard Model (CMSSM), predict a substantial amount of events containing leptons, while the largest fraction of Standard Model background events -which are QCD interactions -gets strongly reduced by requiring isolated leptons. The analyzed data was taken in 2011 and corresponds to an integrated luminosity of approximately L = 1 fb −1 . The center-of-mass energy of the pp collisions was √ s = 7 TeV.

Abstract:The Nucleic Acid Package (NUPACK) is a growing software suite for the analysis and design of nucleic acid systems. The NUPACK web server (http://www.nupack.org) currently enables:• Analysis: thermodynamic analysis of dilute solutions of interacting nucleic acid strands.• Design: sequence design for complexes of nucleic acid strands intended to adopt a target secondary structure at equilibrium.• Utilities: evaluation, display, and annotation of equilibrium properties of a complex of nucleic acid strands.NUPACK algorithms are formulated in terms of nucleic acid secondary structure. In most cases, pseudoknots are excluded from the structural ensemble.

CMS is a general purpose experiment, designed to study the physics of pp collisions at 14 TeV at the Large Hadron Collider (LHC). It currently involves more than 2000 physicists from more than 150 institutes and 37 countries. The LHC will provide extraordinary opportunities for particle physics based on its unprecedented collision energy and luminosity when it begins operation in 2007.The principal aim of this report is to present the strategy of CMS to explore the rich physics programme offered by the LHC. This volume demonstrates the physics capability of the CMS experiment. The prime goals of CMS are to explore physics at the TeV scale and to study the mechanism of electroweak symmetry breaking-through the discovery of the Higgs particle or otherwise. To carry out this task, CMS must be prepared to search for new particles, such as the Higgs boson or supersymmetric partners of the Standard Model particles, from the start-up of the LHC since new physics at the TeV scale may manifest itself with modest data samples of the order of a few fb −1 or less. The analysis tools that have been developed are applied to study in great detail and with all the methodology of performing an analysis on CMS data specific benchmark processes upon which to gauge the performance of CMS. These processes cover several Higgs boson decay channels, the production and decay of new particles such as Z and supersymmetric particles, B s production and processes in heavy ion collisions. The simulation of these benchmark processes includes subtle effects such as possible detector miscalibration and misalignment. Besides these benchmark processes, the physics reach of CMS is studied for a large number of signatures arising in the Standard Model and also in theories beyond the Standard Model for integrated luminosities ranging from 1 fb −1 to 30 fb −1 . The Standard Model processes include QCD, B-physics, diffraction, detailed studies of the top quark properties, and electroweak physics topics such as the W and Z 0 boson properties. The production and decay of the Higgs particle is studied for many observable decays, and the precision with which the Higgs boson properties can be derived is determined. About ten different supersymmetry benchmark points are analysed using full simulation. The CMS discovery reach is evaluated in the SUSY parameter space covering a large variety of decay signatures.

Interstellar pickup ions accelerated by the termination shock of the solar wind dominate the anomalous cosmic-ray (ACR) intensities observed by the Voyager spacecraft in the outer heliosphere. Using a twodimensional acceleration and propagation model, we derive the relative abundances of these interstellar ACRs and determine the mass dependence of the injection/acceleration efficiency for the diffusive acceleration of H + , He + , N + , O + , and Ne + . The energy spectra of C, Na, Mg, Si, S, and Ar also exhibit ACR increases at low energies. To interpret these observations, we have developed a new set of ionization rates for 11 neutral atoms, H, He, C, N, O, Ne, Na, Mg, Si, S, and Ar at 1 AU, and a new set of filtration factors relating neutral densities in the local interstellar medium to those at the location of the solar wind termination shock. Using the injection/acceleration efficiencies and the Ar filtration factor, we estimate the density of neutral Ar to be ð3:5 AE 1:6Þ Â 10 À7 cm À3 in the local interstellar medium. ACR C may have a significant contribution from interstellar neutral C, but the observed intensities of ACR Na, Mg, Si, and S significantly exceed that expected from interstellar neutrals, providing evidence of another source of pickup ions. One possibility discussed is the recently discovered '' inner source '' of singly charged ions that is thought to be solar wind atoms desorbed from interplanetary dust grains.