This study showed no relationship between lag of accommodation and rate of myopia progression in children with progressing myopia. Different ethnic groups may respond differently to the same size of hyperopic blur.

In a naturalistic environment, auditory cues are often accompanied by information from other senses, which can be redundant with or complementary to the auditory information. Although the multisensory interactions derived from this combination of information and that shape auditory function are seen across all sensory modalities, our greatest body of knowledge to date centers on how vision influences audition. In this review, we attempt to capture the state of our understanding at this point in time regarding this topic. Following a general introduction, the review is divided into 5 sections. In the first section, we review the psychophysical evidence in humans regarding vision’s influence in audition, making the distinction between vision’s ability to enhance versus alter auditory performance and perception. Three examples are then described that serve to highlight vision’s ability to modulate auditory processes: spatial ventriloquism, cross-modal dynamic capture, and the McGurk effect. The final part of this section discusses models that have been built based on available psychophysical data and that seek to provide greater mechanistic insights into how vision can impact audition. The second section reviews the extant neuroimaging and far-field imaging work on this topic, with a strong emphasis on the roles of feedforward and feedback processes, on imaging insights into the causal nature of audiovisual interactions, and on the limitations of current imaging-based approaches. These limitations point to a greater need for machine-learning-based decoding approaches toward understanding how auditory representations are shaped by vision. The third section reviews the wealth of neuroanatomical and neurophysiological data from animal models that highlights audiovisual interactions at the neuronal and circuit level in both subcortical and cortical structures. It also speaks to the functional significance of audiovisual interactions for two critically important facets of auditory perception—scene analysis and communication. The fourth section presents current evidence for alterations in audiovisual processes in three clinical conditions: autism, schizophrenia, and sensorineural hearing loss. These changes in audiovisual interactions are postulated to have cascading effects on higher-order domains of dysfunction in these conditions. The final section highlights ongoing work seeking to leverage our knowledge of audiovisual interactions to develop better remediation approaches to these sensory-based disorders, founded in concepts of perceptual plasticity in which vision has been shown to have the capacity to facilitate auditory learning.

The human brain retains a striking degree of plasticity into adulthood. Recent studies have demonstrated that a short period of altered visual experience (via monocular deprivation) can change the dynamics of binocular rivalry in favor of the deprived eye, a compensatory action thought to be mediated by an upregulation of cortical gain control mechanisms. Here, we sought to better understand the impact of monocular deprivation on multisensory abilities, specifically examining audiovisual temporal perception. Using an audiovisual simultaneity judgment task, we discovered that 90 minutes of monocular deprivation produced opposing effects on the temporal binding window depending on the eye used in the task. Thus, in those who performed the task with their deprived eye there was a narrowing of the temporal binding window, whereas in those performing the task with their nondeprived eye there was a widening of the temporal binding window. The effect was short lived, being observed only in the first 10 minutes of postdeprivation testing. These findings indicate that changes in visual experience in the adult can rapidly impact multisensory perceptual processes, a finding that has important clinical implications for those patients with adult-onset visual deprivation and for therapies founded on monocular deprivation.