Intraosseous hibernoma is an uncommon brown fat tumor that with about 2-dozen case reports described in the literature. Hibernomas are more commonly found in soft tissues of the thigh, shoulder, and back. However, more cases of intraosseous hibernomas are coming to light as a result of work-up due to pain or as an incidental lesion finding. Herein, we present a case of a thoracic intraosseous hibernoma suspicious for an isolated ovarian cancer metastasis, successfully treated with radiofrequency ablation and kyphoplasty.
Primary hyperparathyroidism is most commonly caused by adenoma formation in one of the 4 parathyroid glands. The presence of ectopic parathyroid tissue is relatively common and can lead to difficulties in identification and treatment if affected by adenoma. This report describes the case of a 45-year-old female who presented 10 years status post thyroidectomy with symptomatic hyperparathyroidism and found to have ectopic parathyroid adenoma in the anterior mediastinum. Parathyroid scintigraphy with 99m-Technetium sestamibi and computed tomography were used for localization of the adenoma to a 1.9-centimeter para-aortic nodule. Computed tomography-guided transsternal cryoablation was subsequently performed for treatment, with intraoperative evaluation of serum parathyroid and calcium levels for confirmation. This case highlights that a sharp increase in parathyroid hormone immediately after cryoablation is not necessary for successful confirmation of the procedure. It additionally contributes to the growing literature on computed tomography-guided cryoablation as a legitimate alternative to surgery for treatment of ectopic parathyroid adenoma.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.