No abstract

Introduction: In recent year, the incidence of sepsis and urosepsis has even increased, but the associated mortality has decreased suggesting improved management of patients. It is proven that the larger the stones, the greater the chance of acquiring infection (6%-10%), as well as an increased chance of postoperative sepsis. Objective: To assess evaluation the pattern of urosepsis and bacteriuria in patients undergoing PCNL and URS. Methods: This cross sectional study was carried out in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh during the period of January 2018 to December 2019. Sampling technique was purposive and sample size was 71. Among them 24 patients for PCNL and 48 patients for URS were selected by selection criteria. Data were collected by interview of the patients, clinical examinations and laboratory investigations using the research instrument. Data were processed and analyzed using software SPSS (Statistical Package for Social Sciences) version 19.0. Incidence of bacteriuria and urosepsis were measured according to urine and blood culture report. Sensitivity pattern was also observed. Results: According to this study, the incidence of bacteriuria and urosepsis were (16.90%) and (5.6%) respectively, Of the 71 patients, 12 (16.90%) exhibited bacterial growth on urine culture, These 12 patients were then subjected to blood culture and 4(33.3%) of them were found positive. Most (83.4%) of the urine and blood infections (75%) were caused by E. coli. Some widely used antibiotics like moxicillin, Cephalexin and Ciprofloxacin were found 100% resistant in urine culture. Few sensitive antibiotics were Tobramycin (100 %), Amikacin and Ceftazidime (75%). Almost same sensitivity pattern was found in blood culture. In urosepsis, as in other types of sepsis. Urosepsis after PCNL and URS is an important and potentially catastrophic complication. Percuteneousne phrolithotomy (PCNL), Ureterorenoscopy (URS) occurs frequently in this .........