The monotosylates obtained by treatment of α- and β- cyclodextrin with p- methylbenzenesulfonyl chloride reacted with ammonia to give the title compounds. These amines are of unusually low basicity , with pKa values of 8.70 and 8.72, respectively. In water at 25°, the hydrochloride salt of the amine derived from β- cyclodextrin is approximately 40 times more soluble than β-cyclodextrin and, through complexation, the salt increases the solubility of Nabumetone over 800 times.
The reaction between RuCl (PPh3)2(η-C5H5) and LiC6H4Me-p afforded Ru (C6H4Me-p)(PPh3)2(η-C5H5) (76%), structurally characterized by a single-crystal X-ray study at c. 295 K. Crystals are triclinic, Pī , a 16.607(4), b 11.397(3), c 11.076(5)Ǻ, α 94.90(3),β 99.52(3), γ 90.43(2)°, Z 2; R was 0.036 for 6246 'observed' diffractometer reflections. The p-tolyl moiety is σ-bonded to the ruthenium with an Ru-C bond length of 2.122(3)Ǻ. This value is compared with others found for Ru-C(spn) bonds (n=1-3) in σ-bond complexes; these range from 2.013(6) to 2.18Ǻ.
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