The current study presents a radiological water-quality assessment on 64 spring water samples from four Romanian counties. The study area is abundant in CO2-rich spring waters consumed by locals and tourists. Gross alpha activities ranged between 21 ± 2 and 7530 ± 658 mBq L−1, with 27% of the samples exceeding the WHO threshold. Gross beta values ranged from 40 ± 2 to 5520 ± 430 mBq L−1, with 29% exceeding the recommended values. Radionuclide activities fluctuated between 0.6 ± 0.08 and 81 ± 6 Bq L−1 for 222Rn, 15 ± 2 to 1154 ± 112 mBq L−1 for 226Ra, and from 18 ± 2 to 64 ± 5 mBq L−1 for 210Po. The annual effective doses attributed to radium varied between 0.002 and 0.23 mSv yr−1.

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Targeting sonic hedgehog pathway in combination with proton radiation or gamma irradiation decreases viability of glioma cell lines .

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Targeting sonic hedgehog pathway in combination with proton radiation or gamma irradiation decreases viability of glioma cell lines .