Cyclosporine is an immunomodulatory medication that impacts T-lymphocyte function through calcineurin inhibition and suppression of IL-2 expression. Oral cyclosporine at low doses (1-3 mg/kg/d) is one of the more common systemic treatment options for moderate to severe atopic dermatitis. At these doses it has been shown to have therapeutic benefit in several skin conditions, including chronic spontaneous urticaria, 1 psoriasis, 2 and atopic dermatitis. 3 When used at higher doses for conditions such as glomerulonephritis or transplantation, adverse effects may be notable, and close monitoring Magnetic resonance imaging of the brain obtained in the emergency department at the time of presentation showed innumerable peripherally distributed foci of microhemorrhage and vasogenic edema within the left parietal-occipital-temporal lobes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.