Results: After ESWT we observed a rapid and persistent reduction of RSS and decrease of VAS. There was no difference in skin thickness before and after ESWT; however we observed a more regular skin structure and an improvement in skin vascularization 90 days after treatment. EPCs and CECs increased 60 and 90 days after treatment, while serological biomarkers showed no variation before and after therapy.
Conclusions: ESWT resulted in an improvement of VAS, RSS and of skin vascularscore. An increase of CECs and EPCs was also observed after therapy.
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