BackgroundObservational studies report that as students transfer from secondary school to university, there is a tendency to gain weight. This phenomenon is known as the “Freshman 15” in North America, referring to the claim that on average weight gain is 15 lb (6.8 kg) in the first year of university. Studies since 1985 have mostly found weight gains ranging from 1 kg to 6 kg. Our meta-analysis aimed to update the literature on the “Freshman 15” in the first year of university. We also aimed to explore weight gain in only those who gained weight and perform several subgroup analyses. Given adolescent weight gain is highly linked to overweight and obesity in adults, a better understanding of university student weight gain is crucial if we are to combat the rising adult obesity prevalence.MethodsWe conducted a search on six standard electronic databases (including PubMed, Embase, PsycInfo) from 1980 to 2014. Only peer reviewed articles with data from longitudinal studies were included. Screening was performed by two reviewers. The quality of papers was assessed and data extraction was done with a systematic approach.ResultsThirty two studies were included and 22 studies (5549 students) were included in a pooled mean meta-analysis as they reported standard errors. The overall pooled mean weight gain was 1.36 kg (3lbs) (95 % CI: 1.15 – 1.57) over an average of 5 months. A majority of students, 60.9 %, gained weight during freshman year and these on average gained 3.38 kg (7.5lbs) (95 % CI: 2.85 – 3.92).ConclusionFreshman weight gain is an issue with almost two thirds of students gaining weight. Students who gained weight, gained it at rates much faster than in the general population. Despite most universities having some health promotion policies, we denote a consistent weight gain in university students across several countries.

BackgroundActive tuberculosis (TB) disease can impose substantial morbidity, while treatment for latent TB infection (LTBI) has frequent side effects. We compared health-related quality of life (HRQOL) between persons diagnosed and treated for TB disease, persons treated for LTBI, and persons screened but not treated for TB disease or LTBI, over one year following diagnosis/initial assessment.MethodsParticipants were recruited at two hospitals in Montreal (2008–2011), and completed the Short Form-36 version 2 (SF-36) at baseline, and at 1, 2, 4, 6, 9, and 12 months thereafter. Eight domain scores and physical and mental component summary (PCS and MCS, respectively) scores were calculated from responses. Linear mixed models were used to compare mean scores at each evaluation and changes in scores over consecutive evaluations, among participants treated for TB disease and those treated for LTBI, each compared to the control group.ResultsOf the 263 participants, 48 were treated for TB disease, 105 for LTBI, and 110 were control participants. Fifty-four percent were women, mean age was 35 years, and 90% were foreign-born. Participants treated for TB disease reported significantly worse mean scores at baseline compared to control participants (mean PCS scores: 50.0 vs. 50.7; mean MCS scores: 46.4 vs. 51.1), with improvement in mean MCS scores throughout the study period. Scores reported by participants treated for LTBI and control participants were comparable throughout the study.ConclusionTB disease is associated with decrements in HRQOL as measured by the SF-36. This is most pronounced during the weeks after diagnosis and treatment initiation, but is no longer evident after two months.Electronic supplementary materialThe online version of this article (doi:10.1186/s12955-015-0250-4) contains supplementary material, which is available to authorized users.

BackgroundWeight change in first year university students, often referred to as ‘Freshman 15’, has been shown to be a common problem in North America. Studies have reported weight gain to be between 1 kg and 4 kg over the academic year and a recent meta-analysis found a mean gain of 1.34 kg and that 61 % of students gained weight. A limited number of studies have investigated weight change in England and large scale studies are needed to understand better weight change trends and to conduct subgroup analyses. This is important in the context of rising obesity prevalence, especially as behaviours and unhealthy weight in early adulthood often remains over the lifetime.MethodsWe recruited students across 23 universities in England to complete a web-based survey at three time points in 2014–2015: beginning of academic year, December, end of academic year. Students were asked to self-report height and weight. We calculated weight change of each student between time points and conducted t-tests and pared analysis of variance to investigate the effect of time, sex and initial BMI. We also investigated weight change amongst weight gainers and in weight losers separately.ResultsWe followed 215 students over three time points and found a mean weight change of 0.98 kg (95%CI 0.49–1.47) over a mean length of 34 weeks of follow-up. The weight change rate was not significantly different over different terms. Over 51 % of the sample gained more than 0.5 kg by the end of the academic year, with a mean gain of 3.46 kg. Female weight gainers had a significantly lower baseline weight than non-weight gaining females. Twenty-five percent of the sample lost more than 0.5 kg with a mean of −3.21 kg. Within weight losers, males lost significantly more weight than females.ConclusionOur findings reinforce that the first year of university is a crucial time in the life of students during which the majority tend to gain weight. However, we also found that 25 % lost weight, indicating that 75 % of students undergo a meaningful weight change in their first year. Universities must recognise their role in promoting healthy weight maintenance.

Treatment for TB disease had a substantial negative impact on health utility, particularly during the first 2 months of treatment. However, treatment for LTBI did not have a substantial impact.