Background: Traumatic brain injury is a common cause of death in Colombia. The aim of this study was to evaluate the management of traumatic brain injury patients in Colombia. Materials and methods:This study was conducted through a survey sent to 100 general practitioners in Colombia through an electronic format. Results:Over the period of the study, data collected were about 59 physicians consecutively. The 31% of the respondents knew protocols for the management of traumatic brain injury. Conclusion:Traumatic brain injury is one of the most important reasons for consultations in the emergency services in Colombia. We observed significant differences in the initial management of patients with this kind of injury. It requires the establishment of standard protocols and transmission thereof. The implementation of these strategies will contribute to a better patient outcome in Colombia. RESUMENAntecedentes: La lesión cerebral traumática es una causa común de muerte en Colombia. El objetivo de este estudio fue evaluar la manejo de los pacientes con lesiones cerebrales traumáticas en Colombia. Materiales y métodos:El estudio se realizó a través de un encuesta enviada a 100 médicos generales en Colombia a través de formato electrónico.Resultados: Durante el período del estudio, los datos recogidos fueron aproximadamente 59 médicos consecutiva. El 31% de los encuestados sabía protocolos para el manejo de la lesión cerebral traumática.Conclusión: La lesión cerebral traumática es una de las más razones importantes para las consultas en los servicios de emergencia en Colombia. Se observaron diferencias significativas en la inicial manejo de los pacientes con este tipo de lesión. Se requiere que el establecimiento de protocolos y la transmisión del mismo estándar. La implementación de estas estrategias contribuirá a una mejor la evolución del paciente en Colombia. Palabras claves:Lesión traumática del cerebro, La gestión de emergencias, Traumatismo craneoencefálico, Injur head.
Experimental studies in animals demonstrate the ability of the bone marrow stem cells to differentiate in cardiomyocytes, vascular endothelium cells and smooth muscle cells. There is evidence that these cells can regenerate infarcted myocardium and induce myogenesis and angiogenesis. Clinical studies in humans suggest the feasibility and safety of the utilization of the stem cells to recovery the ventricular function in patients with acute myocardial infarction. We report the first experience in Colombia using autologous bone marrow cells for cardiomyoplasty in isquemic heart disease. This report shows the two months follow-up of four patients, three with acute myocardial infarction of the anterior myocardial wall and one patient with severe chronic isquemic heart disease. Extensive myocardial damage demonstrated by absence of viability in scintigraphic images and ejection fraction less than 40%. The patients received an optimum postinfarction medical treatment, successful coronary percutaneous intervention (three patients) or direct intramyocardial injection (one patient) to transfer of autologous bone marrow cells mobilised with granulocyte-colony stimulating factor during five days. Demographics and results The exercise capacity improve importantly, evidenced by increase in contractility, the six minutes test, the treadmill exercise time and the functional capacity in METS. There were not changes in the myocardial perfusion at two months follow-up, there were not complications related to the cellular transplant or the utilization of the granulocyte-colony stimulating factor. This is the first experience in Colombia with the bone marrow cells and selective intracoronary transplantation for myocardial regeneration and angiogenesis. We observed functional recovery of the left ventricle, improvement in the exercise capacity without adverse effects or complications related to the therapy. Patient # 1 2 3 4 MI= myocardial infarction, IHD= isquemic heart disease, B/A= before/after 2 months, EF= eyection fraction, ESV=end systolic volume Age/sex 51/M 23/M 59/M 53/M Diagnosis acute MI acute MI acute MI chronic IHD Diagnosis to transplant 3 weeks 2 weeks 4 weeks > 1 year CD34 dose 19.7x10(6) 16.8x10(6) 19.5x10(6) 21.7x10(6) EF% B/A 36/43 26/40 40/41 45/55 ESV (cc) B/A 80/60 116/103 65/70 101/84 METS B/A 4/14 4/17 5/12 5/14 6-min test (mts) B/A 420/540 216/462 260/450 414/727
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