BACKGROUND AND OBJECTIVES: Chronic neuropathic pain has a multifactorial origin and several coping strategies. The objective of this study was to identify, analyze the different coping strategies for chronic neuropathic pain, relate them with sociodemographic characteristics, pain intensity, and alexithymia. METHODS: A descriptive and cross-sectional study involving 61 patients with neuropathic pain who attended the Pain Clinic from August to December 2017. The instruments used to collect the data of patients with neuropathic pain were a semi-structured interview, the Douleur Neuropathique 4 Questions questionnaire, the Alexithymia Scale, and the Problems Coping Mode Scale. RESULTS: Of the 61 patients with neuropathic pain, the majority were female, with a mean age of 50.67±13.12 years, low schooling, with a spouse, with diseases as the leading cause of pain, positive attitudes to cope with neuropathic pain despite the physical problems such as major changes after pain. CONCLUSION:The results of the present study allowed us to conclude that the coping strategies of patients with neuropathic pain, according to the application of the Alexithymia Scale and the Problems Coping Mode Scale, that the highest scores were in religious practices, social support and focus on the problem. The alexithymia of this group was higher, especially in the subgroup of men with chronic neuropathic pain.