In order to obtain functionalized naphthoquinones, a systematic study of the Kochi-Anderson procedure for the alkylation of quinones is presented. While linear amino acids of different lengths were good substrates for this decarboxylation procedure, chiral α-amino acids were unsuccessful substrates. The best reaction conditions were evaluated with β-alanine and then applied to a series of carboxylic acids to obtain chemical diversity on the naphthoquinones. We ob-
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