Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = −0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics.
Three-dimensional Pd@Pt core−shell nanostructures with controllable shape and composition were synthesized by using a one-step microwave heating method. The nanostructures with the morphology, structure, and composition being easily controlled through adjusting the molar ratio between Pt and Pd precursor were characterized by transmission electronic microscopy (TEM), scanning electronic microscopy (SEM), X-ray powder diffraction (XRD), and energy-dispersive X-ray (EDX) techniques. In addition, the electrocatalytic characteristics of these prepared Pd@Pt electrocatalysts with different Pd/Pt molar ratio for oxygen electro-reduction reaction (ORR) and methanol electro-oxidation reaction (MOR) were systematically investigated by voltammetry. The results show that Pd@Pt electrocatalysts exhibit higher catalytic activity than pure Pd and pure Pt catalysts for both the ORR and MOR, and the highest activity is obtained at the Pd@Pt electrocatalyst with a Pd/Pt molar ratio of 1:3. This result demonstrates that a higher performance of ORR and MOR could be realized at the novel core−shell electrocatalyst while Pt utilization also could be diminished. This method may open a general approach for the shape-controlled synthesis of bimetallic Pt−M nanocatalysts, which can be expected to have promising applications in fuel cells.
Based on extensive field research in China during 2005–2010, this article aims to explore the determinants of unionization in the Chinese context. We find that managerial strategies toward union organizing and functioning have been critical in determining unionization outcomes in Chinese enterprises. While various environment pressures may impose critical constraints on these strategies, managerial industrial relations ideologies are central in shaping these strategies when environment pressures barely exist or are bearable by management. Our study makes the first effort in exploring industrial relations ideologies in China and contributes to better understanding of unionization in the Chinese workplace.
Recent studies have found that viral myocarditis (VMC) associated with coxsackievirus B3 (CVB3) causes autophagy activation after infection, but the specific mechanism is not clear. The present study demonstrated that the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway participates in CVB3-induced autophagy. We found that the light chain 3 (LC3)-II/LC3-I ratio was increased and p62 and p-mTOR were altered at different times during CVB3 infection. To further assess the effects of this signaling pathway on CVB3 infection and viral replication, we selected 24 h post-inoculation (h.p.i.) as our research time point to conduct our next study. We inhibited the function of PI3K, Akt1 and mTOR. The outcome showed that inhibition of PI3K with ZSTK474 alleviated autophagy and decreased CVB3 mRNA replication and VP1 expression. Inhibition of mTOR with rapamycin promoted autophagy and viral mRNA replication but did not impact VP1 expression. Inhibition of Akt with MK2206 aggravated autophagy induced by viral infection. In our research, p62 exhibited a decrease at the beginning of infection but then increased as infection time increased. This finding may serve as a clue to elucidate the function of autophagy at different times of infection. However, the details merit further study. In conclusion, our findings suggest that the PI3K/Akt/mTOR signaling pathway participates in the process of autophagy induced by CVB3 infection. This finding may provide a new perspective of CVB3-induced autophagy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.