A novel and efficient electrophilic fluorination of secondary phosphine oxides with Selectfluor has been achieved. This transformation provides direct access to phosphoric fluorides in up to 92% yield under mild conditions. In addition, P-O bond construction via a one-pot coupling process of secondary phosphine oxides with water or alcohols in the presence of Selectfluor leads to the formation of phosphinic acids or phosphinates in up to 96% yield.

A direct route to alkylphosphonates has been achievedviaDDQ-mediated cross-dehydrogenative coupling between diarylphosphine oxides and xanthene derivatives.

The novel P-arylation of dialkyl phosphites and secondary phosphine oxides with arynes has been achieved. The reactions produce dialkyl arylphosphonates in 71-99% yield and tertiary phosphine oxides in 68-92% yield under mild conditions.

α-Sulfenylation of carbonyl compounds has been achieved via Cs2CO3-promoted aerobic cross-dehydrogenative coupling of thiophenols with active methylene compounds.

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