Nonafluoro-t-butyl propyl (1), allyl (2), and propargyl (3) ethers as well as 1,2-bis(nonafluoro-t-butoxy)ethane (4), 1,3-bis(nonafluoro-t-butoxy)-propane (5), and 1,4-bis(nonafluoro-t-butoxy)-butane (6) were prepared by the reaction of sodium nonafluoro-t-butoxide (7) with the corresponding alkyl halides in good yields. Their fluorous partition coefficients and toxicity were also investigated. Computational studies have shown that 4, 5 and 6 exist in a monomeric form in MeOH-CF 3 C 6 F 11 and they likely aggregate to form oligomers in PhCH 3 -CF 3 C 6 F 11 . † Electronic supplementary information (ESI) available. See

The synthesis, some of the properties and the applications of fluorous phosphines in biphasic, organometallic and organo-catalysis were reviewed.