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Rapid growth in capacity makes flow-based microfluidic biochips a promising candidate for biochemical analysis because they can integrate more complex functions. However, as the number of components grows, the total length of flow channels between components must increase exponentially. Recent empirical studies show that long flow channels are vulnerable due to blocking and leakage defects. Thus, it is desirable to minimize the total length of flow channels for robustness. Also, for timing-sensitive biochemical assays, increase in the longest length of flow channel will delay the assay completion time and lead to variation of fluid, thereby affecting the correctness of outcome. The increasing number of components, including the pre-placed components, on the chip makes the flow channel routing problem even more complicated. In this paper, we propose an efficient obstacleavoiding rectilinear Steiner minimum tree algorithm to deal with flow channel routing problem in flow-based microfluidic biochips. Based on the concept of Kruskal algorithm and formulating the considerations as a bi-criteria function, our algorithm is capable of simultaneously minimizing the total length and the longest length of flow channel.

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In this paper, we present MtDetector, a high performance marine tra c detector that can predict the destination and the arrival time of travelling vessels. MtDetector accepts streaming data reported by the moving vessels and generates continuous predictions of the arrival port and arrival time for those vessels. To predict the destination for a ship, MtDetector builds a neural network for every port and infers the arrival port for vessels based on their departure port. For the arrival time prediction, we derive informative features from training data and apply Deep Neural Network (DNN) to estimate the traveling time. MtDetector is built on top of DtCraft [1, 2], a high-performance distributed execution engine for stream programming. By utilizing the task-based parallelism in DtCraft, Mt-Detector can process multiple predictions concurrently to achieve high throughput and low latency. CCS CONCEPTS• Theory of computation → Distributed computing models; • Computing methodologies → Neural networks; • Software and its engineering → Cloud computing;

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