This study aimed to understand nurses' experiences of moral distress when caring for elderly dementia patients who reside in long-term care centers. Methods: Colaizzi's phenomenological approach was used for this study. The participants included eight nurses. Semi-structured in-depth interviews were used to collect data from February to August 2019. Results: Three categories emerged from the analysis. The nurses reported experiences of moral distress when caring for older adults with dementia. Theses experiences included "worrying about sincere care", "a sense of guilt about task-oriented care", "a feeling of helplessness because they cannot advocate care". Seven theme clusters and 17 themes emerged in this study. The participants stated feeling conflicted about the meaning of care when they know secondary problemes will occur, but inevitably choose the next-best care option. The nurses could not provide proper care to their patients due to their overburdened workloads. The participants experienced a sense of guilt for caring only about the task at hand, without empathy. They felt helpless because that could not represent human rights and felt the gap between principle and reality as a nurse. Conclusion: These results suggest nurses' moral distress must be considered to improve elderly dementia care. It is ethically and morally necessary for education programs to focus on caring for elderly dementia patients, and these findings can guide the program's content and direction.
Background and Objectives Nasal polyp can be defined as a chronic inflammatory disease of the paranasal sinus mucosa, histologically characterized by massive edema and accumulaiton of eosinophils. Eosinophils in the inflammatory tissue release mediators capable of causing tissue damage. The recruiment of eosinophils to the site of inflammation are mediated by a number of chemokines, particularly eotaxin, RANTES, MCP-3, MCP-4. The receptor that mediates these action has been known CCR3 which are expressed highly on the surface of eosinophils. This study was designed to determine whether there is increased expression of CCR3 in nasal polyp and whether this is associated with eosinophil count in histopathology. Materials and Methods We performed the light microscopic examination for histopathology and the analysis of CCR3 mRNA with RT-PCR in 20 nasal polyps, 7 allergic inferior turbinate mucosas and 6 hypertrophic inferior turbinate mucosas. Results The number of eosinophil were higher in nasal polyps than in allergic inferior turbinate mucosas and hypertrophic inferior turbinate mucosas. The expression levels of CCR3 mRNA were higher in nasal polyps than in allergic inferior turbinate mucosas and hypertrophic inferior turbinate mucosas. The infiltrating eosinophils were correlated the expression levels of CCR3 mRNA p 0.001, r 0.877 . Conclusion These results suggest that CCR3 is a host factors highly specialized for eosinophil recruitment in inflammation, and may be good targets for the development of selective drug for inflammatory disease where eosinophils contribute to pathogenesis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.