The aim of this work was to investigate the dosimetric characteristics of radiophotoluminescent glass dosimeter (RPLGD) for high energy photon beams in both flattening filter mode and flattening filter free (FFF) mode. The dosimetric characteristics of RPLGD model GD-302M were studied in 6 MV photon beams for the reproducibility of dosimeter reader, uniformity and reproducibility of RPLGD, dose linearity (range from 1 to 20 Gy), repetition rate, and angular dependence. In addition, the energy responses were observed in flattening filter mode (6 MV, 10 MV, and 15 MV) from Varian Clinac Cseries and FFF mode (6 MV_FFF and 10 MV_FFF) from Varian TrueBEAM system. The FGD-1000 reader system exhibited stable readout. The entire number of 100 RPLGDs showed good uniformity and reproducibility within ±1.5%. Furthermore, the signal from RPLGD demonstrated a linear proportion to the radiation dose (r = 0.999), and no energy dependence was observed. For repetition rate response of flattening filter mode and FFF mode, the maximum error of relative response to 400 MU/min were 0.977 ±0.006 and 0.986±0.017, respectively. The response of RPLGD reached 1.00 at ±30°g antry angle while at +90°gantry angle, the RPLGD response was 8% lower compared to-90°gantry angle because the attenuation effect was more pronounced. We conclude that the RPLGD is capable to measure radiation dose since it provides desirable dosimetric properties such as good uniformity and reproducibility of RPLGD including the reader system. Besides, RPLGD is available with small active readout area which adds benefit for clinical implementation in radiotherapy, especially for advanced techniques.

Introduction:The well-being of breast cancer patients is essential, especially fertility in patients of reproductive age. The objective of this study was to estimate the radiation doses to the ovaries and uterus for different treatment techniques of breast cancer irradiation using radio-photoluminescent glass dosimeters (RPLDs). Methods: A Farmer-type ionisation chamber (IBA FC-65G) and RPLDs were used to measure in-and out-of-field radiation doses in a solid water phantom. The field sizes were set to 10 9 10 cm 2 and 8 9 17 cm 2 with the central axis at out-of-field measurement distances of 30 or 50 cm. The Rando phantom's left breast was planned using four different techniques: two tangential standard fields with and without electronic tissue compensator (E-comp) techniques, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). The radiation doses in the ipsilateral ovary, contralateral ovary and uterus were measured using RPLDs. Results: The percentage ratio of out of field to in field was affected by distance from the central axis to the point of measurement, in addition to the field sizes associated with collimator scatter. Advanced techniques such as IMRT and VMAT produced higher doses to the ovaries and uterus. The estimated results of the worst-case scenario for the ipsilateral ovary, contralateral ovary and uterus were 0.84% (42 cGy), 0.62% (31 cGy) and 0.76% (38 cGy), respectively, for a 5000 cGy prescription dose. Conclusion:The lowest to highest out-of-field radiation doses to the ovarian and uterine organs from breast irradiation were the two tangential field techniques, VMAT and IMRT. These advanced techniques yielded higher radiation leakage, which potentially contributed to the out-of-field radiation dose.

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