Anxiety and depression were frequently observed in Korean IBS patients and were related to the severity of their symptoms and the impairment of the patient's QOL. Our data suggest that assessing anxiety and depression is important when evaluating IBS patients.

No abstract

No abstract

Satellite data has been used to ascertain trends and correlations between climate change and vegetation greenness in Asia. Our study utilized 33-year (1982-2014) AVHRR-GIMMS (Advanced Very High Resolution Radiometer - Global Inventory Modelling and Mapping Studies) NDVI3g and CRU TS (Climatic Research Unit Time Series) climate variable (temperature, rainfall, and potential evapotranspiration) time series. First, we estimated the overall trends for vegetation greenness, climate variables and analyzed trends during summer (April to October), winter (November to March), and the entire year. Second, we carried out correlation and regression analyses to detect correlations between vegetation greenness and climate variables. Our study revealed an increasing trend (0.05 to 0.28) in temperature in northeastern India (bordering Bhutan), Southeast Bhutan, Yunnan Province of China, Northern Myanmar, Central Cambodia, northern Laos, southern Vietnam, eastern Iran, southern Afghanistan, and southern Pakistan. However, a decreasing trend in temperature (0.00 to -0.04) was noted for specific areas in southern Asia including Central Myanmar and northwestern Thailand and the Guangxi, Southern Gansu, and Shandong provinces of China. The results also indicated an increasing trend for evapotranspiration and air temperature accompanied by a decreasing trend for vegetation greenness and rainfall. The temperature was found to be the main driver of the changing vegetation greenness in Kazakhstan, northern Mongolia, Northeast and Central China, North Korea, South Korea, and northern Japan, showing an indirect relationship (R=0.84-0.96).

No abstract

Background/AimsEndoscopic submucosal dissection (ESD) has been regarded as a curative treatment for early gastric cancer (EGC) in indicated cases. The aim of this study was to evaluate the nationwide long-term clinical outcomes of ESD for EGC in Korea.MethodsA prospective multicenter cohort study was performed to evaluate the long-term efficacy of ESD for EGC within pre-defined indications at 12 institutes in Korea. The cases that met the expanded criteria upon pathological review after ESD were followed for 5 years. The primary outcome was 5-year disease specific free survival.ResultsSix hundred ninety-seven patients with 722 EGCs treated with ESD were prospectively enrolled and followed for 5 years. Complete resection was achieved in 81.3% of the cases, and curative resection was achieved in 86.1%. During the 5-year follow-up, the overall survival rate was 96.6%, and the disease specific free survival rate was 90.6%. Local recurrence developed in 0.9%, and metachronous tumor development occurred in 7.8%; both conditions were treated by endoscopic or surgical treatment. Distant metastasis developed in 0.5% during follow-up.ConclusionsESD showed excellent long-term clinical outcomes and can be accepted as a curative treatment for patients with EGC who meet the expanded criteria in final pathology studies.

As most of the forest fires in South Korea are related to human activity, socio-economic factors are critical in estimating their probability. To estimate and analyze how human activity is influencing forest fire probability, this study considered not only environmental factors such as precipitation, elevation, topographic wetness index, and forest type, but also socio-economic factors such as population density and distance from urban area. The machine learning Maximum Entropy (Maxent) and Random Forest models were used to predict and analyze the spatial distribution of forest fire probability in South Korea. The model performance was evaluated using the receiver operating characteristic (ROC) curve method, and models’ outputs were compared based on the area under the ROC curve (AUC). In addition, a multi-temporal analysis was conducted to determine the relationships between forest fire probability and socio-economic or environmental changes from the 1980s to the 2000s. The analysis revealed that the spatial distribution was concentrated in or around cities, and the probability had a strong correlation with variables related to human activity and accessibility over the decades. The AUC values for validation were higher in the Random Forest result compared to the Maxent result throughout the decades. Our findings can be useful for developing preventive measures for forest fire risk reduction considering socio-economic development and environmental conditions.

Background/AimsEndoscopic submucosal dissection (ESD) is an effective treatment for early gastric cancer (EGC) that has demonstrated a minimal risk of lymph node metastasis in retrospective studies. We sought to prospectively evaluate the short-term outcomes of ESD treatment in EGCs.MethodsA prospective multicenter cohort study of neoplasms 3 cm or less in diameter at endoscopic size evaluation was performed in 12 Korean ESD study group-related university hospitals and the National Cancer Center. Resected specimens were evaluated by the central pathologic review board.ResultsA patient cohort (n=712) with a total of 737 EGCs was analyzed. The margin-freeen bloc resection rate was 97.3%, and curative resection of 640 lesions (86.8%) was achieved. Lower curative resection rates were associated with lesions 2 to 3 cm in size prior to ESD compared with lesions 2 cm or less in size (78.6% vs 88.1%, respectively, p=0.009). Significant factors associated with noncurative resection were moderately or poorly differentiated histological type, posterior wall tumor location, tumor size larger than 3 cm, ulceration, and submucosal invasion. Delayed bleeding occurred in 49 patients (6.9%), and 12 patients (1.7%) exhibited perforations.ConclusionsESD is an effective treatment with a high curative resection rate for EGCs that meets relatively conservative pre-ESD indications. Long-term survival outcomes should be evaluated in follow-up studies.