Background In 2040, the older population's growth rate in sub-Saharan Africa (SSA) will be faster than those experienced by developed nations since 1950. In preparation for this growth, the National Institute on Aging commissioned the National Academies' Committee on Population to organize a workshop on advancing aging research in Africa. This meeting provided a platform for discussing some areas requiring improvement in aging research in SSA regions. We believed that conducting a systematic review of peer-reviewed articles to set priorities for aging research in SSA is warranted. Therefore, this article is the first in a Four-Part series that summaries the types and trends of peer-reviewed studies in SSA. Methods This systematic mapping review followed the Search-Appraisal-Synthesis-Analysis Framework. We systematically searched multiple databases from inception till February 2021 and included peer-reviewed articles conducted with/for older adults residing in SSA. Conventional content analysis was employed to categorize studies into subject-related areas. Results We included 512 studies (quantitative = 426, qualitative = 71 and mixed-method = 15). Studies were conducted in 32 countries. Quantitative studies included were observational studies: cross-sectional (n = 250, 59%), longitudinal (n = 126, 30%), and case-control (n = 12, 3%); and experimental studies: pre-post design (n = 4, 1%), randomized control trial (RCT, n = 12, 3%); and not reported (n = 21, 5%). Fifteen qualitative studies did not state their study design; where stated, study design ranged from descriptive (n = 14, 20%), ethnography (n = 12, 17%), grounded theory (n = 7, 10%), narrative (n = 5, 7%), phenomenology (n = 10, 14%), interpretative exploratory (n = 4, 6%), case studies (n = 4, 6%). Of the 15 mixed-method studies, seven did not state their mixed-method design. Where stated, design includes concurrent (n = 1), convergent (n = 1), cross-sectional (n = 3), informative (n = 1), sequential exploratory (n = 1) and retrospective (n = 2). Studies were classified into 30 (for quantitative studies) and seven (for qualitative and mixed-method) subject-related areas. HIV/AIDs-related and non-communicable diseases-related studies were the most predominant subject-related areas. No studies explored the transdisciplinary co-production of interventions. Conclusions There are glaring gaps in ageing research in SSA, especially mixed-methods and RCTs. A large number of studies focused on HIV/AIDs and non-communicable disease-related studies. National and international funding agencies should set up priority funding competitions for transdisciplinary collaborations in ageing research.
Background The quality assessment provides information on the overall strength of evidence and methodological quality of a research design, highlighting the level of confidence the reader should place on the findings for decision making. This paper aimed to assess the quality (methodology and quality of reporting) of ageing studies in Sub-Saharan Africa (SSA). Method This paper is the second of a Four-Part Series paper of a previous systematic mapping review of peer-reviewed literature on ageing studies conducted in SSA. We updated the literature search to include additional 32 articles, a total of 544 articles included in this paper. Downs & Black checklist, Case Report guidelines checklist, the 45-items Lundgren et al. checklist, and the Mixed Method Appraisal Tool were used to assess the methodological quality of quantitative, case reports, qualitative, and mixed-method studies. Quality assessment was piloted and conducted in pairs for each study type. Depending on the checklist, each study was classified as excellent, good, fair, or poor. Result Of the 544 articles, we performed the quality assessment of a total of 451 quantitative studies [Randomized control trials (RCTs) and pre-post (n=15), longitudinal (n=122), case-control (n=15) and cross-sectional (n=300); 4 case reports, 74 qualitative and 15 mixed-method studies. Only 20.4% (n=111) articles were of high quality [one RCT, 27 longitudinal, 4 case-control, 48 cross-sectional studies, 19 qualitative, and 12 mixed-method studies]. The remaining 433 were rated as moderate quality (n=292, 53.7%), fair quality (n = 96, 17.7%) and poor quality (n = 45, 8.2%). Most (80%) quantitative articles’ sample size is small, resulting in insufficient power to detect a clinically or significant important effect. Three-quarter (75%) of the qualitative studies did not report their research team characteristics and a reflexivity component of the 45-items Lundgren et al. checklist. Mixed-method studies with low quality did not report the qualitative studies properly. Conclusion We conclude that the methodological and quality reporting of published studies on ageing in SSA show variable quality, albeit primarily moderate quality, against high quality. Studies with a large sample size are recommended, and qualitative researchers should provide a section on research team members’ characteristics and reflexivity in their paper or as an appendix.
Purpose: This study investigated the relationship between estimated oxygen consumption (VO2max) and handgrip strength (HGS) among healthy young Nigerian adults. Methods: This was a cross sectional study, which involved 400 volunteers (171 males; 229 females) aged between 18–40years. Participants’ HGS was assessed using a CAMRY EH-101 hand dynamometer while VO2max was estimated using a standard formula that includes measurement of resting heart rate. Demographic data was summarized using percentages, mean and standard deviation. Physical activity level of the participants was assessed using long form of the International Physical Activity Questionnaire. Independent t-test was used to compare the mean values of the variables between male and female participants. Pearson’s correlation was used to determine the strength of relationship between estimated VO2max and HGS, while multiple regression analysis was conducted to determine the predictors of estimated VO2max using HGS as well as body mass index (BMI), physical activity (PA) level, age and sex as co‐variates. Level of significance was set at p<0.05. Results: HGS, VO2max and PA level were significantly (p= 0.001) different between male and female participants. There was a significant moderate correlation between HGS and VO2max (r= 0.40, p= 0.001). The results of the regression analysis showed that HGS is not significant predictor of estimated VO2max; whereas, sex, BMI and PA level were significant predictors of estimated VO2max. Conclusion: Although HGS is moderately correlated with estimated VO2max, HGS may not be a relevant tool for predicting estimated VO2max in healthy young adults.
Study aim: To summarize the current state and quality of qualitative research conducted by physiotherapists in sub-Saharan Africa (SSA). Methods:We systematically searched multiple databases from 2000 till December 2020 and included peer-reviewed qualitative studies conducted by physiotherapists in SSA countries. Two reviewers independently screened citations, extracted data, and assessed the quality of the included studies using the 45-items checklist by Lundgren et al. (2012).Conventional content analysis was employed to create physiotherapy subject areas from the included studies. Results:We included 114 studies, a majority of 84 (74%) conducted in South Africa.Included studies were categorized into five subject areas: sports (n=2), disability (n=16), professional practice (n=24), education and training (n=36) and care provision (n=36).We rated 74 (65%), 29 (25%), and 11 (10%) of the included research as low reporting quality, moderate-and high reporting quality, respectively. There was a significant lack of reporting on researchers' team characteristics, reflexivity and member checking. Conclusion:We conclude that the reporting of published qualitative studies in SSA show variable quality, albeit mostly low, focused mainly on care provision, education and training. Physiotherapy-researchers are encouraged to report reflexive practice and member checking when conducting qualitative research.
Background As the physiotherapy profession gradually evolves into a more autonomous profession, physicians continue to play a major role in the clinical practice of physical therapists globally, particularly as a source of patient referral. Therefore, an evaluation of Nigerian physiotherapists’ (NPTs) perception of physician’s referral (PR) of patients for physiotherapy may be a critical indicator of the relationship between the two professionals in the Nigerian health sector. The objective of the study was to determine the perception of Nigerian NPTs on the PR of patients for physiotherapy and the influence of demographic characteristics on the perception. The study was an online survey involving one hundred and fifty-four respondents. The instrument for the study was an 11-item self-developed questionnaire with two domains: demographics and perception. The participants were blind respondents reached through different physiotherapists’ WhatsApp platforms in Nigeria. The responses were collated electronically after 2 months and analyzed with the Statistical Package for Social Sciences (SPSS) version 23. Results The respondents have a negative perception of the 9 out of the 11-questionnaire items that were used to test the physiotherapists’ perception of the physicians’ referral of patients for physiotherapy in Nigeria health facilities. There was no significant difference (p>0.05) across the respondents’ gender, place of employment, areas of specialization, and educational qualifications and the respondents’ perception of doctors’ referrals of patients for physiotherapy. However, there was a significant difference (p<0.05) in each of the participants’ perceptions across the respondents’ years of practice, with the participants who had less than 5 years of practice having the least score. Conclusions Nigerian physiotherapists have a negative perception of physicians’ referral of patients for physiotherapy, and the perception was only influenced by the years of practice of the respondents.
Certain cranial neural crest cells are uniquely endowed with the ability to make skeletal cell types otherwise only derived from mesoderm. As these cells migrate into the pharyngeal arches, they downregulate neural crest specifier genes and upregulate so-called ectomesenchyme genes characteristic of skeletal progenitors. While both external and intrinsic factors have been proposed as triggers of this transition, the details remain obscure. Here we report the Nr2f nuclear receptors as novel intrinsic activators of the ectomesenchyme program: zebrafish nr2f5 single and nr2f2;nr2f5 double mutants show marked delays in upregulation of ectomesenchyme genes such as dlx2a, prrx1a/b, sox9a, twist1a, and fli1a, and in downregulation of sox10, which is normally restricted to early neural crest and non-ectomesenchyme lineages. Mutation of sox10 fully rescued skeletal development in nr2f5 single but not nr2f2;nr2f5 double mutants, while the initial ectomesenchyme delay persisted in both. Sox10 perdurance thus antagonizes the recovery but does not explain the impaired ectomesenchyme transition. Unraveling the mechanisms of Nr2f function will help solve the enduring puzzle of how cranial neural crest transition to the skeletal progenitor state.
Background Studies to determine gender response to transcutaneous electrical nerve stimulation (TENS) application on individuals who presented with post-injection sciatic pain (PISP) following gluteal injection is not common. A total of 40 subjects comprising 20 males and 20 females who were purposively recruited and conveniently assigned to group A (male) and group B (female) completed the study. Acupuncture-like TENS (AL-TENS) was applied on the 20 male and 20 female subjects, 1 h per session, 3 times per week for the 10 weeks the study lasted. Result The pre-intervention baseline scores for the two groups were 8.80 + 1.05 (Female) and 8.60 + 1.27 (Male). The result revealed that after 10 weeks of intervention the VAS scores were 2.60+ 3.28 (p < 0.001) and 2.40 + 3.28 (p < 0.001) for the female and male subjects, respectively. The mean comparison of the female mean VAS scores (2.60 + 3.28) and male VAS scores 2.40 + 3.25 after 10 weeks of AL-TENS intervention shows no statistically significant difference (p > 0.85) in pain intensity (pain perception). Conclusions There was no gender variation in pain perception in subjects with post-injection sciatic pain (PISP) following gluteal muscle injection after 10 weeks of AL-TENS application. Therefore, gender-based variation should not be considered when applying AL-TENS as an instrument of intervention in subjects with PISP. Trial registration PACTR2018050034082
Introduction: Physiotherapists are exposed to contracting infectious diseases because of the level of contact they have with patients in the course of performing their statutory clinical duties. Objective: The major objective of the study is to determine the availability and utilization of personal protective equipment (PPE) by Nigerian physiotherapists during the COVID-19 pandemic. Methods: One hundred and eighty-one (181) Nigerian physiotherapists participated in an online survey using Google Form application that lasted between September 2020 and October 2020. The data collection instrument was a 22-item close-ended online questionnaire with three domains: demographics, availability of PPE, and utilization of PPE. The authors made use of different WhatsApp platforms hosting only physiotherapists as a means of reaching out to the respondents. Data obtained from the study were analyzed using STATA 13. A p-value of less than 0.05 was considered to be statistically significant (confidence level = 95). Results: The result of the study shows there were high availability and utilization of facemasks and hand gloves for the Nigerian physiotherapists during the period of COVID-19 pandemic in the different health facilities; it also shows there was low availability of apron and poor availability of protective eye shield/goggles and shoes during the same period. The finding also showed there was low utilization of apron, protective glasses and shoes by the Nigerian physiotherapists during the peak of COVID-pandemic. Conclusions: Most Nigerian physiotherapists had more face masks and hand gloves during COVID-19 pandemic than they had protective aprons, goggles and shoes. Also, there was high utilization of facemasks and the hand gloves more than an apron, eye shield and protective shoes because the more the PPE was available the more the utilization by the Nigerian Physiotherapists.
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