It is a challenge to prepare photonic crystal (PC) automotive coatings via spraying colloidal solutions because the fast fabrication tends to produce amorphous photonic crystals with faint colors. Here, a two‐step spraying process followed by thermal curing is developed to prepare waterproof PC coatings with bright, uniform, and angular‐dependent structural colors. The solvents in PC paint are studied to achieve a quick formation of liquid PC intermediate, which transformed into a highly crystalline PC coating. Thanks to the narrow and intense reflections, the as‐made coatings present colors with high saturation, including the red/yellow/green/blue colors achieved by tuning the particle size, and many spectral/non‐spectral colors via the mixing of base colors. Meanwhile, patterned or fully covered PC coatings with good chemical and mechanical stability can be prepared on different substrates, where the shiny colors changing with the viewing angles or the surface curvatures offer a new choice for personalized automotive coatings.

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Objective Endothelial lipase (EL) is a key determinant in plasma HDL-C. However, functional roles of EL on the development of atherosclerosis have not been clarified. We investigated whether hepatic expression of EL affects plasma lipoprotein metabolism and cholesterol diet-induced atherosclerosis. Approach and Results We generated transgenic (Tg) rabbits expressing the human EL gene in the liver and then examined the effects of EL expression on plasma lipids and lipoproteins and compared the susceptibility of Tg rabbits to cholesterol diet-induced atherosclerosis with non-Tg littermates. On a chow diet, hepatic expression of human EL in Tg rabbits led to remarkable reductions in plasma levels of total cholesterol, phospholipids, and HDL-cholesterol compared with non-Tg controls. On a cholesterol-rich diet for 16 weeks, Tg rabbits exhibited significantly lower hypercholesterolemia and less atherosclerosis than non-Tg littermates. In Tg rabbits, gross lesion area of aortic atherosclerosis was reduced by 52%, and the lesions were characterized by fewer macrophages and smooth muscle cells compared with non-Tg littermates. Conclusions Increased hepatic expression of EL attenuates cholesterol diet-induced hypercholesterolemia and protects against atherosclerosis.