Purpose Lower limb varicose veins have a significant effect upon the quality of life and a considerable socioeconomic impact despite their relatively benign nature. The aim of this study is to compare the effects of various therapeutic strategies among patients with varicose veins to surgical ligation and vein stripping on the basis of quality of life. Methods PubMed/Medline and Scopus databases were systemically searched from 1 January 2000 until 23 December 2015 for studies reporting outcome on the quality of life of different treatment techniques for varicose veins. We used Cohen's d to make the outcomes of the reported scales comparable. Heterogeneity was calculated with the use of the Q statistic and the I. Results A total of 1047 participants were randomized across all analyzed trials. The number of participants in a single trial ranged from 30 to 308. The majority of participants in any trial were C2 on the CEAP scores. Overall, the quality of evidence was low. For the meta-analysis performed at 12 months postintervention (seven studies, n = 1047 patients) and after random effects meta-analyses due to high heterogeneity, no differences are observed between intervention and surgical ligation and vein stripping. The pooled estimate is -0.001 and the 95% confidence interval is -0.069 to 0.067 with a p = 0.98. In the case of the 24 months, postintervention analysis (six studies, n = 840 patients) the inference is almost identical. The effect of various interventional modes of treatment compared to surgical ligation and vein stripping is negligible in terms of clinical outcomes and quality of life so that surgical ligation and vein stripping versus the other interventional procedures were equally effective approaches to treat great saphenous vein incompetence in terms of quality of life measurements. Conclusion The procedures were at least equally efficient in treating patients with varicose vein disease in terms of quality of life assessment tools at 12 and 24 months compared to surgical ligation and vein stripping.

Objective:To study time-trends in vascular access surgery. Design: Prospectively registered data. Material and methods: The Swedish vascular registry (Swedvasc) was searched for haemodialysis access operations (HAO) 1987(HAO) -2006 Results: 12,342 open and endovascular operations were identified. Eighty-five percent of HAO 2004HAO -2006 were reported to the registry. The median age of patients having their first HAO increased from 56 to 68 during the first decade (p Ͻ 0.0001), then remained stable. The frequency of diabetes increased from 12% in 1987 to 32% in 2006 (p Ͻ 0.0001). The percentage of first HAO of total workload decreased from 76% to 48%. The percentage of first HAO performed as vein fistulas remained unchanged. The number of patients recorded for ten or more previous HAO increased over time. Percutaneous angioplasties increased during the last decade.Of 4706 patients operated on with primary radiocephalic AV-fistulas, 2933 (62%) were operated only once. Analysis of 3739 subsequent operations in 1773 patients disclosed that at the tenth operation vein was still used in 54%. With an increasing number of operations, arterial inflow shifted towards a more proximal position.Conclusions: Over time, the patients undergoing HAO became older and more often diabetic, reoperations increased. Despite these circumstances, vascular surgeons perform AV-fistulas without grafts in most patients.

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This analysis supports the use of BBAVF early in difficult access cases prior to the use of prosthetic grafts. However, the latter conclusion is debatable due to heterogeneity, small size and non-randomised design of the included studies.