Both plastic (permanent) and hypercompliant deformation of the lamina cribrosa and anterior scleral canal wall are present in young adult monkey eyes with early experimental glaucoma. These findings suggest that damage to the ONH connective tissues occurs early in the monkey model of experimental glaucoma.

On February 19, 2003, a 3-year-old child was sent downstairs to retrieve a toy. Shortly after, her guardian heard a noise and ran to find her lying at the bottom of the split-foyer stairs. She was rushed to the hospital immediately by paramedics. She died five days later and the cause of death determined was brain herniation due to anoxic/ischemic brain injury. The objective of this research was to determine which fall scenario(s) matched the trauma sustained utilizing scientifically proven quantitative measures.