Grover's disease is an entity reported worldwide and recognized as a common disease since Grover first described it in 1970. Its cause remains obscure, but hospitalized, febrile and sun-damaged patients are particularly prone. It is frequently associated with some other skin diseases, including eczemas, psoriasis and solar keratoses. Acantholysis is the universal histological finding in all the varying clinical presentations. Treatment in the past has been ad hoc, but topical therapy, acitretin and phototherapy can suppress symptoms.

A series of twenty-four cases of transient acantholytic dermatosis (TAD) is presented. All patients were male and their eruptions tended to be more persistent than those of previously reported cases. The epidermal changes included four patterns of acantholysis, of which the pemphigus-like pattern was associated with the more persistent eruptions. Although twenty-three of the twenty-four patients had other actinic-associated skin lesions, no direct relationship between the onset of TAD and episodes of excessive sun exposure was found. Oral vitamin A treatment has been effective in some cases.