This review of the geology, geophysics, and origin of the unconformity-associated uranium deposit type is focused on the Athabasca Basin. Pods, veins, and semimassive replacements of uraninite (var. pitchblende) are located close to unconformities between late Paleo-to Mesoproterozoic conglomeratic sandstone basins and metamorphosed basement rocks. The thin, overall flat-lying, and apparently unmetamorphosed but pervasively altered, mainly fluvial strata include red to pale tan quartzose conglomerate, sandstone, and mudstone. Beneath the basal unconformity, red hematitic and bleached clay-altered regolith grades down through chloritic altered to fresh basement gneiss. The highly metamorphosed interleaved Archean to Paleoproterozoic granitoid and supracrustal basement gneiss includes graphitic metapelitic that preferentially hosts reactivated shear zones and many deposits. A broad variety of deposit shapes, sizes and compositions ranges from monometallic and generally basement-hosted veins to polymetallic lenses located just above or straddling the unconformity, with variable Ni, Co, As, Pb and traces of Au, Pt, Cu, REEs, and Fe. Résumé Cet examen de la géologie, de la géophysique et de l'origine des gîtes d'uranium associés à des discordances est focalisé sur le bassin d'Athabasca. Les minéralisations d'uraninite (variété pechblende) qui prennent la forme de lentilles, de filons ou de corps semi-massifs de remplacement se situent près de la discordance entre des grès conglomératiques de bassin du Paléoprotérozoïque tardif au Mésoprotérozoïque et les roches du socle métamorphisées. La succession sédimentaire de bassin est mince, repose dans l'ensemble à plat, est apparemment non métamorphisée, mais profondément altérée, et se compose principalement d'unités fluviatiles constituées de conglomérats quartzeux, de grès et de mudstones de couleur rouge à chamois pâle. Sous la discordance marquant la base de la succession sédimentaire, un régolite hématitique rouge, décoloré par endroits par une altération argileuse, passe progressivement vers les profondeurs du socle à des gneiss chloritisés puis à des gneiss non altérés. Les roches très métamorphisées du socle, formées d'une intercalation de gneiss granitoïdes et de gneiss supracrustaux de l'Archéen au Paléoprotérozoïque, incluent des métapélites graphitiques qui renferment de manière préférentielle des zones de cisaillement réactivées et un grand nombre de gîtes. Les gîtes sont de formes, de dimensions et de compositions très variées, passant de minéralisations monométalliques, généralement sous forme de filons encaissés dans le socle, à des lentilles polymétalliques présentant des concentrations variables de Ni, Co, As, Pb et des traces de Au, Pt, Cu, de terres rares et de Fe, qui se situent à cheval sur la discordance ou à peu de distance au-dessus. Definition Unconformity-associated uranium deposits are pods, veins, and semimassive replacements consisting of mainly uraninite dated mostly 1600 to 1350 Ma, and located close to basal unconformities between Proterozoi...

BackgroundTo address the growing GP workforce crisis, NHS England (NHSE) launched the Clinical Pharmacists in General Practice scheme in 2015. The NHSE scheme promotes a newer, patient-facing role for pharmacists and, currently, there is little insight into the role and activities undertaken. All scheme pharmacists are enrolled on the general practice pharmacist training pathway (GPPTP).AimTo investigate the role evolution and integration of clinical pharmacists in general practice in England.Design and settingLongitudinal survey of all phase 1 GPPTP registrants working in general practice at start of (T1) and 6 months into (T2) training.MethodAn online longitudinal survey was administered to all phase 1 GPPTP registrants (n = 457) at T1 and T2, measuring their perceived knowledge, skill, and confidence, activities performed, and perceptions of practice integration, environment, and support. Descriptive statistics and non-parametric tests were conducted.ResultsResponse rates were 46% (T1) and 52% (T2); 158 participants completed both questionnaires. Perceived knowledge, skill, and confidence levels increased significantly from T1 to T2 for all areas, except for managing acute or common illness. Scope of practice increased significantly, particularly in patient-facing activities. Sharing office space with administrative staff was common and 13% of participants reported having no designated work area. Perceived integration at T2 was fairly high (median = 5 on a scale of 1–7) but GP clinical support was ‘too little’ according to one-third of participants.ConclusionFindings show not only patient-facing role expansion, but also practice environment and support issues. Pharmacists may appreciate more GP time invested in their development. Practices need to be realistic about this support and not expect an immediate reduction in workload.

Community pharmacists' theoretical understanding of self-care was not reflected in the ways that they portrayed their contributions to self-care support. The current ways in which community pharmacy delivers its services for patient care may need to be re-configured in order to fit into the holistic self-care support paradigm.

Redesigned health systems could meet the rising demand for healthcare, with community pharmacy currently an underused resource for the treatment and management of patients requiring urgent care. This study aimed to investigate whether a training intervention delivered over 2 days to community pharmacists resulted in behaviour and practice change. Validated measures of psychological motivation and

The results suggest that the marketing of the new COX-2 inhibitors and the patients' anticipation of a safe and effective treatment have overcome the geographical boundaries of Queensland. Both areas had very high rates of uptake of the prescribing of these new drugs.