[reaction: see text] Terminal alumination of alkynes by DIBALH or trimethylaluminum can be performed in a simple manner in the presence of a small amount of triethylamine. This new Lewis-base-catalyzed process delivers mixed alkynyldialkylalanes of great interest, without the need of an initial deprotonation step with lithium or sodium derivatives followed by a transmetalation.
Reactions of organo-metal compounds O 0350Synthesis and Reactivity of Mixed Alkynylalanes by Direct Triethylamine-Catalyzed Alumination of Terminal Alkynes. -A general synthesis of aluminum acetylides is developed. This pathway involves a new Lewis base catalyzed metalation reaction of terminal alkynes, delivering a reactive mixed alkynylorganoaluminum species without the need of prior preparation of their lithium or sodium salt. -(FEUVRIE, C.; BLANCHET, J.; BONIN*, M.; MICOUIN, L.; Org. Lett. 6 (2004) 14, 2333-2336; Lab. Chim. Ther., CNRS, Fac. Sci. Pharm. Biol., Univ. R. Descartes, F-75270 Paris, Fr.; Eng.) -Steudel 43-064
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