BASIC AND TRANSLATIONAL PANCREAS pancreatic cancer cells showed increased loading of integrin a6b4 into sEVs-a process that required CD82. CONCLUSIONS: Human pancreatic ductal adenocarcinoma has reduced levels of PRKD1 compared with nontumor pancreatic tissues. Loss of PRKD1 results in reduced phosphorylation of cortactin in pancreatic cancer cell lines, resulting in increased in F-actin at the plasma membrane and increased release of sEVs, with altered content. These sEVs promote metastasis of xenograft and pancreatic tumors to lung in mice.

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This paper presents a single-copter localization system as a first step towards a scalable multihop drone swarm localization system. The drone was equipped with ultrawideband (UWB) transceiver modules, which can be used for communication, as well as distance measurement. The location of the drone was detected based on fixed anchor points using a single type of UWB transceiver. Our aim is to create a swarm localization system that enables drones to switch their role between an active swarm member and an anchor node to enhance the localization of the whole swarm. To this end, this paper presents our current baseline localization system and its performance regarding single-drone localization with fixed anchors and its integration into our current modular quadcopters, which was designed to be easily extendable to a swarm localization system. The distance between each drone and the anchors was measured periodically, and a specially tailored gradient descent algorithm was used to solve the resulting nonlinear optimization problem. Additional copter and wireless-specific adaptations were performed to enhance the robustness. The system was tested with a Vicon system as a position reference and showed a high precision of 0.2 m with an update rate of <10 Hz. Additionally, the system was integrated into the FINken copters of the SwarmLab and evaluated in multiple outdoor scenarios. These scenarios showed the generic usability of the approach, even though no accurate precision measurement was possible.

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Abstract-The Carolo-Cup competition conducted for the eighth time this year, is an international student competition focusing on autonomous driving scenarios implemented on 1:10 scale car models. Three practical sub-competitions have to be realized in this context and represent a complex, interdisciplinary challenge. Hence, students have to cope with all core topics like mechanical development, electronic design, and programming as addressed usually by robotic applications.In this paper we introduce the competition challenges in detail and evaluate the results of all 13 participating teams from the 2014 competition. For this purpose, we analyze technical as well as non-technical configurations of each student group and derive best practices, lessons learned, and criteria as a precondition for a successful participation. Due to the comprehensive orientation of the Carolo-Cup, this knowledge can be applied on comparable projects and related competitions as well.