The efficacy of problem-solving therapy (PST) to reduce psychological distress was assessed among a sample of 132 adult cancer patients. A second condition provided PST for both the patient and a significant other. At posttreatment, all participants receiving PST fared significantly better than waiting list control patients. Further, improvements in problem solving were found to correlate significantly with improvements in psychological distress and overall quality of life. No differences in symptom reduction were identified between the 2 treatment protocols. At a 6-month follow-up, however, patients who received PST along with their significant other reported lower levels of psychological distress as compared with members of the PST-alone condition on approximately half of the outcome measures. These effects were further maintained 1-year posttreatment.

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Previous research has indicated that one's sense of humor serves as a moderator of the deleterious effects of negative stressful life events. However, because this research has been only cross-sectional in nature, such conclusions remain tentative. The purpose of this study was to provide for a more rigorous test of the humor as a stress-buffer hypothesis by using a prospective design that also attempted to control for the variance attributable to prior level of distress. Additionally, two measures of humor were included to increase the construct validity of the findings. Results from a series of regression analyses indicated that humor served as a moderator of stress for depressive, but not anxiety, symptomatology, regardless of the measure of humor that was used in the analyses. Implications of these findings for future research are noted.

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