The idea of a digital twin as a virtual representation of a product is not new. However, the modern IoE (Internet of Everything) technology is able to cover a new dimension in terms of monitoring and controlling an operating state of a products or process. The potential is high to reach a new maturity level in all PLM processes. Unfortunately, it is a very complex topic and has a high impact on internal and external processes. The technical challenges are spread in different domains. The business value is hard to see. Therefore the risks are also high and a well-grounded strategy is necessary. This includes an organic growth with customer benefit and a consistent change management in the company.Besides a successful implementations of digital twins this guide provides a pragmatic approach to get access to the digital twin technology. It covers the range from the conceptual understanding of a digital twin to a successful implementation with a prototype.