This paper reviews electrospray ionization mass spectrometry (ESI-MS) as an analytical tool for the investigation of nonbiological materials. The fundamentals of the method are briefly described and principles of the interpretation of ESI mass spectra are explained. Differences in comparison to biochemical applications of ESI-MS are discussed. Selected examples show how ESI-MS can be used for the investigation of synthetic monomers, oligomers, and polymers, especially in cases where other analytical methods fail. Acta Polymer., 48,513-526 0 WILEY-VCH Verlag GmbH, D-69451 Weinheim 1997 0323-7648/97/12 12-05 13$17.50+.50/0 513 514 Saf, Mirtl, Hummel Acta Polymer., 48,5 13 -526 (1997) Acta Polymer., 48,5 13 -526 ( 1997)Electrospray ionization mass spectrometry as an analytical tool for non-biological ...
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Electrospray ionization mass spectrometry (ESI-MS) was
used for the characterization of
oligomers which were prepared by ring-opening metathesis polymerization
(ROMP) of methyl N-(1-phenylethyl)-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate
(1), employing molybdenum alkylidene initiators
of the type
Mo(CH(t-Bu))(NAr)(OR)2 (Ar
= 2,6-di(isopropyl)phenyl, R =
C(CH3)3 (I),
C10H17 (II), and
CCH3(CF3)2 (III)). ROMP was
terminated with acetone/water (99/1, v/v), the solvent also used for
ESI-MS.
The oligomers (2) had different alkylidene end groups
derived from the active species: neopentylidene
(from the catalyst), isopropylidene (reaction with acetone) and
(2-(methoxycarbonyl)-5-methyl-N-(1-phenylethyl)pyrrolid-3-yl)methylidene (reaction with water,
hydrogenation product). Metathesis equilibration and intramolecular reactions of the active species with ester
groups, resulting in the formation of
cyclic products, were found. The influence of the initiator
structure and the reaction time t
R is
discussed.
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