Two heptamethine cyanine dyes suitable for labeling of biomolecules at a primary amino group with a near-infrared chromophore/fluorophore (λ max /(λ em = 800/830 nm and 837/864 nm) have been synthesized from readily available starting materials. Despite the high molecular complexity of intermediate and final products, all these compounds have been obtained in an analytically pure form by using crystallization only.
Cyanine and polymethine dyes T 1300 Synthesis of Water-Soluble Near-Infrared Cyanine Dyes Functionalized with [(Succinimido)oxy]carbonyl Group. -Title compounds (I), which are suitable for labeling of biomolecules at a primary amino group with a near-infrared chromophore/ fluorophore, are prepared from readily available starting materials. -(STREKOWSKI*, L.; MASON, C. J.; LEE, H.; GUPTA, R.; SOWELL, J.; PATONAY, G.; J. Heterocycl. Chem. 40 (2003) 5, 913-916; Dep. Chem., Ga. State Univ., Atlanta, GA 30303, USA; Eng.) -F. Santoso 11-159
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