Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living animals, enabling future identification of new biomarkers.
Süße Hilfe: Sialinsäuren spielen bei vielen Wirt‐Pathogen‐Erkennungsereignissen eine Rolle und markieren embryonale und bösartige Gewebe, was zu einem großen Interesse an Verfahren zur Anreicherung und Identifizierung sialylierter Glycoproteine in komplexen Geweben führt. Nun kann N‐(4‐Pentinoyl)mannosamin zur metabolischen Markierung sialylierter Glycoproteine in lebenden Tieren genutzt werden.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.