Metabolic syndrome (MetS) is a group of risk factors which increase morbidity and mortality for cardiovascular disease and diabetes. The prevalence of MetS has been on the rise. No previous study has described the prevalence of MetS in Yogyakarta Special Region and its components. The study aim was to determine the prevalence of MetS and it's components in Yogyakarta Special Region, Indonesia. A total of 766 male and female subjects aged ≥40 were analyzed in this retrospective study based on secondary data from the Indonesian Family Life Survey batch 4 (IFLS 4). MetS was defined by International Diabetes Federation (IDF) criteria with ethnicity-specific values for waist circumference. Prevalence of MetS and characteristic of each component of MetS were expressed as mean or %. The difference of the MetS components was evaluated by t-test and chi-square. Prevalence of MetS in Yogyakarta Special Region was 13.19%. The most common of MetS component was hypertension (60.44%), followed by dyslipidemia (56.27%), central obesity (32.38%), pro-inflammatory state (15.71%) and insulin resistance (0.78%). There was a higher prevalence of MetS in females compared to males (15.88 vs 10.19%), pre-elderly compared to the elderly (13.90 vs 12.19%), Javanese compared to other ethnicities (13.23 vs 10.00%), and urban compared to rural populations (15.06 vs 8.37%). In conclusion,the prevalence of MetS in Yogyakarta Special Region is 13.19% with hypertension and dyslipidemia as the most common components. ABSTRAKSindrom metabolik (SM) merupakan sekelompok faktor risiko yang meningkatkan morbiditas dan mortalitas penyakit kardiovaskuler dan diabetes. Prevalensi SM mengalami peningkatan. Tidak ada penelitian sebelumnya yang memaparkan prevalensi SM dan komponennya di Daerah Istimewa Yogyakarta. Tujuan penelitian ini untuk menentukan prevalensi SM dan komponennya di Daerah Istimewa Yogyakarta, Indonesia. Sebanyak 766 subyek laki-laki dan perempuan berumur ≥40 dianalisis pada penelitian retrospektif ini berdasarkan data sekunder dari Survei Rumah Tangga Indonesia angkatan 4 (SAKERTI 4). SM ditetapkan dengan kriteria International Diabetes Federation (IDF) dengan nilai spesifik etnisitas untuk lingkar perut. Prevalensi SM dan komponen SM dievaluasi J Med Sci, Volume 49, No. 3, 2017 July:
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