Background Quality of life (QOL) is now concerned worldwide in cancer clinical fields and the specific instrument FACT-Hep (Functional Assessment of Cancer Therapy- Hepatobiliary questionnaire) is widely used in English-spoken countries. However, the specific instruments for hepatocellular carcinoma patients in China were seldom and no formal validation on the Simplified Chinese Version of the FACT-Hep was carried out. This study was aimed to validate the Chinese FACT-Hep based on Combinations of Classical Test Theory and Generalizability Theory. Methods The Chinese Version of FACT-Hep and the QLICP-LI were used to measure QOL three times before and after treatments from a sample of 114 in-patients of hepatocellular carcinoma. The scale were evaluated by indicators such as validity and reliability coefficients Cronbach α, Pearson r, intra-class correlation (ICC), and standardized response mean. The Generalizability Theory (G theory) was also applied to addresses the dependability of measurements and estimation of multiple sources of variance. Results The Internal consistency Cronbach’s α coefficients were greater than 0.70 for all domains, and test-retest reliability coefficients for all domains and the overall were greater than 0.80 (exception of emotional Well-being 0.74) with the range from 0.81 to 0.96. G-coefficients and Ф-coefficients confirmed the reliability of the scale further with exact variance components. The domains of PWB, FWB and the overall scale had significant changes after treatments with SRM ranging from 0.40 to 0.69. Conclusions The Chinese version of FACT-Hep has good validity, reliability, and responsiveness, and can be used to measure QOL for patients with hepatocellular carcinoma in China.
Objective To apply generalization theory and item response theory to analyze the entries of the QLICD-NS (V2.0), a quality of life scale for patients with nephrotic syndrome of chronic diseases. Methods The quality of the scale was measured by applying the overall scores of the generalization theory(GT) as well as the corresponding relative or absolute errors, generalization coefficients and reliability indices. The research also used software of Multilog 7.0 to apply difficulty, discrimination coefficients, and information content of each item of item response theory( IRT). Results The GT results showed an even distribution of the proportion of total score contribution ratio across the 4 domains, except for social functioning. The probability coefficients of all four domains were greater than 0.50. The reliability indices of all domains were greater than 0.5 except for social functioning. The relative and absolute error variances of the four domains were within 0.30. The IRT results showed that the discrimination of the QLICD-NS (V2.0) scale was 0.82, and the items with a good degree of differentiation. Except for entry of TNS7 and TNS8, the difficulty coefficients of the remaining items were between -3.0 and 3.0 and were monotonically increasing. The information content of TNS5 and TNS8 was less than 0.12, and the mean values of information content in the remaining items met the criteria, which can be considered as good quality items. Conclusion The QLICD-NS (V2.0) developed in this study has good performance, but a few items still need further improvement.
Objective To develop and assess the Quality of Life Instruments for Chronic Diseases-Gout (QLICD-GO [V2.0]).Methods The instrument was developed using a programmatic decision-making method to combine the general module of the Quality of Life Instruments for Chronic Diseases and a new specific module. The instrument was assessed by measuring the quality of life of 116 patients with gout.Results The QLICD-GO(V2.0) included 28 items from the general module of chronic diseases and 12 items in three facets from the specific module. In addition to the field of physiological function, the internal consistency reliability of other fields and dimensions of the instrument was > 0.7 and the split-half reliability was > 0.5. Three common factors were extracted from the specific module, with a cumulative variance contribution rate of 57.54%. The standardized response means of the specific module and the whole instrument were 0.94 and 1.20, respectively.Conclusions The QLICD-GO(V2.0) has good reliability, validity, and responsiveness. The instrument comprehensively and objectively reflects the quality of life of patients with gout, and it can be used to assess treatment regimens developed by medical staff.
Doctor-patient trust is the basis of harmonious doctor-patient relationship. Social psychology plays a unique role in interpreting the connotation and construction of doctor-patient trust relationship. From the two levels of doctor-patient interpersonal trust and intergroup trust, this paper summarizes the relevant theoretical viewpoints of social psychology on the construction of doctor-patient trust relationship, and analyzes the key factors affecting doctor-patient interpersonal trust and intergroup trust. On this basis, this paper puts forward the construction path of doctor-patient trust of “interpersonal interaction-emotional communication-interpersonal trust” and “intergroup interaction-social knowledge-intergroup trust”, reveals the interaction mechanism of interpersonal trust and intergroup trust and the circular feedback mechanism between them to promote the formation of doctor-patient trust relationship, and establishes a social psychology model of the formation mechanism of doctor-patient trust relationship.
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