Long-term care for older people with dementia can adversely impact a family caregiver's life. A decrease in their quality of life may compromise the quality of care they provide to older people and their own quality of life. The samples include 76 family caregivers of older people with dementia in Thailand. Six questionnaires and the EuroQoL Five Dimensions Questionnaire were used in data collection. Descriptive and inferential statistics were used in data analysis. The findings revealed that quality

Background Currently, there is no consistent understanding of the relationship between depression and sleep quality in patients with systemic lupus erythematosus (SLE). This study aimed to explore the correlation between depression and sleep quality in SLE patients. Methods Five English (PubMed, Web of Science, EMBASE, Cochrane Library, and CINAHL) databases were systematically searched from inception to January 12, 2021. Two authors independently screened publications and extracted data according to set inclusion and exclusion criteria. Statistical analyses were performed with STATA 16.0. Data were pooled using a random-effects model. Results A total of 9 identified studies matched the inclusion criteria, reporting on 514 patients with SLE in the analysis. A moderate correlation of depression with sleep quality was found (pooled r = 0.580 [0.473, 0.670]). Compared to good sleepers, patients with SLE and poor sleep quality had higher levels of depression (standardized mean difference =  − 1.28 [− 1.87, − 0.69]). Depression was associated with subjective sleep quality (r = 0.332 [0.009, 0.592]), sleep latency (r = 0.412 [0.101, 0.649]), sleep disturbances (r = 0.405 [0.094, 0.645]), daytime dysfunction (r = 0.503 [0.214, 0.711]), the four dimensions of Pittsburgh Sleep Quality Index (PSQI), while no significant correlation was found in the other three PSQI dimensions. Conclusion Depression had a moderate correlation with sleep quality in patients with SLE. Patients with poor sleep quality tended to have higher level of depression than that of good sleepers. Awareness of the correlation may help rheumatology physicians and nurses to assess and prevent depression and improve sleep quality in patients with SLE.

In this cross‐sectional study, we compared preventive behaviors among Thai people aged >60 years of age, with and without stroke risk, in Chiang Mai Province, Thailand, and examined the associations between stroke knowledge and stroke awareness with preventive behaviors in these two groups (n = 422). Participants completed researcher‐developed tools, including the Personal Demographic Questionnaire, the Stroke Knowledge Questionnaire, the Awareness of Stroke Risk and Severity Questionnaire, and the Stroke Preventive Behavior Questionnaire. The findings revealed a significantly higher mean score of preventive behaviors in older people with stroke risk than in those without risk. For people with stroke risk, stroke knowledge did not result in a significant association with stroke‐preventive behaviors, while stroke awareness did. For those without stroke risk, both stroke knowledge and stroke awareness were significantly associated with stroke‐preventive behaviors. Although the stroke‐preventive behaviors of both groups were performed appropriately, it is necessary for people with stroke risk to maintain preventive behaviors, and for health professionals to regularly assess them for stroke symptoms and encourage people to be proactive about stroke‐preventive behaviors.

The quality of life (QOL) of older people with dementia may depend on their care environment.  This cross-sectional descriptive study aims to investigate the QOL of Thai older people with dementia in homes for the aged and those living in their own homes in the community, as well as the discrepancy between the QOL rated by the older people and by caregivers. The samples included 342 participants who met the inclusion criteria. Data were collected using the Quality of Life-Alzheimer’s Disease Scale (QOL-AD) and the EuroQol 5 Dimensions (EQ-5D) Questionnaire Thai Version Scale. Data were analyzed using descriptive statistics, t test, and Pearson’s correlation. The findings revealed that the overall QOL scores of participants in both groups were at a moderate level. Compared with participants in homes for the aged, those living in the community showed higher scores in 7 aspects of QOL-AD, including physical health, energy, living situation, memory, self as a whole, ability to do chores, and ability to make life fun, but lower scores in the aspects of family/members and marriage/closed persons. Self-rated and caregiver-rated scores were significantly different in the aspects of living situation, memory, relationship with family, and marriage/closed persons. The findings imply that health care professionals can also assess the QOL of older people with dementia through self-rating. Further research to find the most effective method for enhancing older peoples’ QOL is needed.

Previous studies on the relationship between the circulating level of interleukin-17 (IL-17) and disease activity in systemic lupus erythematosus (SLE) were contradictory. This study is aimed at quantitatively assessing the correlation between the circulating IL-17 level and disease activity in SLE patients. A systematic search for related literature was conducted via PubMed, Web of Science, EMBASE, and Cochrane Library (up to January 26, 2021). The relationship between circulating IL-17 levels and SLE activity was evaluated using Fisher’s z value, which was then converted to r . The standardized mean difference (SMD) and its 95% confidence interval (CI) were used to describe the difference between the circulating IL-17 level in patients with active and inactive SLE. STATA 16.0 was used to perform statistical analysis. Random-effects model was performed to synthesize data. Twenty-six studies involving 1,560 SLE patients were included in this review. The pooled r value was 0.38 (95% CI: 0.25-0.50; I 2 = 83.8 %, P < 0.001 ) between the SLE activity and circulating level of IL-17. Patients with active SLE had higher level of circulating IL-17 than that of inactive ( pooled   SMD = 0.95 , 95% CI: 0.38-1.53; I 2 = 90.5 %, P < 0.001 ). The subgroup analysis suggested that the region and detection method of circulating IL-17 might not be a source of heterogeneity. No significant publication bias was found. In summary, circulating IL-17 level has a low positive relationship with SLE activity. It is necessary to carefully consider the use of circulating IL-17 as a biomarker of the disease activity in SLE patients. The relationship between the circulating level of IL-17 and SLE activity should be further confirmed in randomized controlled studies.