We herein report the case of an 80-year-old Japanese woman who presented to our hospital with bilateral pain in the shoulders and hips lasting for a month since 2 days after the second dose of the BNT162b2 COVID-19 vaccine. Her physical findings, laboratory data, and ultrasonographic findings of bilateral biceps tenosynovitis and lateral subacromial bursitis were consistent with a diagnosis of polymyalgia rheumatica (PMR). She was successfully treated with oral prednisolone 15 mg/day. Although a causal relationship could not be definitively confirmed, PMR should be considered as a differential diagnosis in cases of persistent myalgia after administration of the BNT162b2 vaccine.
Background This study was aimed to investigate the efficacy of the over‐the‐wire (OTW) microelectrodes catheter in coronary venous system (CVS) mapping and treatment of outflow tract ventricular arrhythmia (OTVA) arising from the vicinity of the left ventricular summit (LVS). Methods Consecutive 62 patients with idiopathic OTVA in whom the OTW microelectrodes catheter was routinely used for CVS mapping were analyzed. CVS mapping was performed for both main trunk (from great cardiac vein to anterior interventricular vein) and branches including the annular branch or septal branch. Results The earliest activation site (EAS) was within the CVS in 21 patients. Among them, the EAS was within the main trunk of the CVS in seven (33%) and within the branch of the CVS in 14 (67%) patients. Radiofrequency catheter ablation was started at an anatomically adjacent site to the EAS, which eliminated OTVA in 16 (76%) patients (the endocardial LVOT in 10 and the aortic sinus of Valsalva in six patients). For the remaining five patients with unsuccessful catheter ablation at an anatomically adjacent site, targeted OTVA was eliminated by catheter ablation at the EAS within the CVS in two patients and by chemical ablation with ethanol injection in one patient, resulting in the overall success rate of 90% (19/21). Conclusion The OTW microelectrodes‐guided ablation of OTVA from the vicinity of the LVS was effective. In maximizing the efficacy of ablation, CVS branch mapping is important since the earliest activation was commonly recorded not in the main trunk but within the branch of the CVS.
Background Subselection inner catheters (Inner‐Cath) are used adjunctively with outer guiding catheters (Outer‐Cath) during cardiac resynchronization therapy (CRT) device implantation. This study aims to investigate the feasibility and efficacy of left ventricular lead placement (LV‐LP) guided by Inner‐Cath alone. Methods A total of 74 patients undergoing de novo CRT implantation were investigated. LV‐LP was initially guided by Inner‐Cath in 42 patients (Inner‐Cath group) and Outer‐Cath in 32 patients (Outer‐Cath group). In the Inner‐Cath group, a 7Fr Inner‐Cath was advanced to the coronary sinus through a 7 Fr sheath inserted in a subclavian vein. In the Outer‐Cath group, 9Fr or 10Fr Outer‐Caths were used. Success rate of LV‐LP, additional use of inner or outer catheters and procedure‐related complications were compared between groups. Results LV‐LP was successful in all patients in the Inner‐Cath group, while LV‐LP had to be abandoned in two patients (6.3%) of the Outer‐Cath group due to CS perforation caused by Outer‐Cath manipulation. Procedure time was significantly shorter in the Inner‐Cath group (148 vs. 168 min; p = .024). Deployment of both an inner and outer cath became necessary less frequently for the Inner‐Cath group (4.8% vs. 56.3%; p < .001). Mechanical CS injuries due to guiding catheter manipulation were only observed in the Outer‐Cath group (0% vs. 15.6%, p = .013). Conclusion LV‐LP guided by Inner‐Cath alone was feasible in over 95% of the patients without severe complications. This methodology for LV‐LP may be preferable in CRT candidates with severe LV dysfunction in terms of shorter procedure time, smaller guiding sheath, and less procedure‐related complications.
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