Point the finger: Zinc‐finger proteins are convenient and site‐selective adaptors for targeting specific locations within DNA‐origami structures. Orthogonal targeting of the specific locations in the structures was demonstrated by using two adaptors, and the application of Escherichia coli lysate that contained the adaptor‐fused proteins successfully afforded the expected protein–DNA assembly.

Fingerzeig: Zinkfingerproteine sind Adaptoren, die Positionen in DNA‐Origami‐Strukturen ortsselektiv ansteuern. Zwei solche Adaptoren können spezifische Positionen in orthogonaler Weise ansteuern, was in Escherichia‐coli‐Lysat, das Fusionsproteine der Adaptoren enthielt, zum Aufbau der erwarteten Protein‐DNA‐Struktur angewendet wurde.

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Many poor-quality medicines are supplied to patients mainly in developing countries. No systematic survey on counterfeit medicines has been conducted in Myanmar since 1999. The purpose of this study was to investigate the current situation of substandard or counterfeit medicines in Myanmar. Samples of oral medicines, cefuroxime axetil (CXM), donepezil hydrochloride (DN) and omeprazole (OM), and injections, ceftriaxone sodium (CTRX), and gentamicin sulfate (GM), were collected from pharmacies, hospitals, and wholesalers in Yangon, Myanmar in 2014. Authenticity and quality were verified. There were 221 (94%) foreign medicines among 235 collected samples. Five samples of GM and 1 DN sample were not registered with the Food and Drug Administration, Myanmar. In quality analysis, 36 samples out of 177 (20.3%) did not pass quantity tests, 27 samples out of 176 (15.3%) did not pass content uniformity tests, and 23 out of 128 samples (18.0%) did not pass dissolution tests. Three of the unregistered GM samples failed in both identification and microbial assay tests. Counterfeit GM is being sold in Yangon. Also, the quality of OM is a matter of concern. Poor-quality medicines were frequently found among the products of a few manufacturers. Regular surveys to monitor counterfeit and substandard medicines in Myanmar are recommended.