In this study, polyethersulfone (PES) was infused with iron nanoparticles (Fe-NPs) obtained from the leaf of pomegranate plant to enhance hydrophilicity of the PES membrane. The resulted nanocomposite Fe-NPs/PES membrane obtained via phase inversion was characterized using a scanning electron microscope (SEM) for the morphology; a texture analyzer for the mechanical strength; an atomic force microscope (AFM) for the surface roughness; and water contact angle measurement for the degree of hydrophilicity. The separation performance of the membrane was evaluated using BTEX-containing wastewater. SEM images show that Fe-NPs were distributed uniformly within the membrane with improved mechanical strength. Mechanical strength of PES was enhanced at increasing Fe-NPs loading from 1.2 MPa for the pure PES to 8.94 MPa for 20 wt.% Fe-NPs loaded membrane. AFM analysis reveals that membrane roughness increased with increase in Fe-NPs loading. Also, the contact angle measurement indicates that the hydrophilicity of the composite membrane was enhanced by the addition of Fe-NPs. The permeation properties reveal that pure water flux of the composite membrane increased with increasing Fe-NPs loading. In addition, the highest BTEX rejection obtained was 64.55% at 10 wt.% Fe-NPs loading when compared to the rejection 41.4% obtained from the pure PES membrane evaluated at similar conditions.