Aim: To determine effects of Gongronema latifolium leaf extract on Malondialdehyde (MDA) levels of wistar rats induced by a toxic dose of Ibuprofen. Material and Methods: Thirty wistar rats were randomly divided into five groups with six rats in each group (n=6); Control (C) received normal feed only. T1 was administered with Gongronema latifolium leaf extract 50 mg/kg BW+ Ibuprofen, T2: Gongronema latifolium extract 100 mg/kg BW+ Ibuprofen, T3: Gongronema latifolium leaf extract 150 mg/kg BW+ Ibuprofen. T4: received Jbruprofen only.This lasted for fourteen days. On the 15th day, blood samples were collected and the level of MDA was then measured. Results: T1, T2, T3 showed significantly decreased MDA levels when compared with theT4 at p < 0.05. Conclusion: Gongronema latifolium extract has an antioxidant effect on the prevention of elevated MDA levels.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.