We evaluated the correlation of the left main coronary bifurcating angle (LCBA) with the severity of coronary atherosclerosis, risk factors of coronary artery disease (CAD) and the feasibility of measuring the LBCA using the axial plane. Coronary Computed tomography angiographies (CTAs) of 313 patients between Nov. 2006 and Oct. 2013 were reviewed and separated into three groups. Group I (211 patients) had significant stenosis (≥50%) of the left anterior descending coronary artery (LAD) and/or left circumflex coronary artery (LCX). Group II (62 subjects) had atherosclerosis without significant stenosis. Group III (40 subjects) had unremarkable coronary CTAs. Both Group I and II patients received conventional catheter angiography to confirm the severities of coronary stenoses. Significant differences were found among the groups with respect to risk factors, such as male gender, hypertension and body mass index. Axial plane measurement was feasible in most patients (82.1%), without significant differences among the groups. The mean LCBA was 84.7° among all patients, and significantly differed among groups I, II and III (87.34°, 81.16° and 75.53°, P < 0.001). The LCBA of group I was significantly higher than group III (P < 0.001) in univariate analysis, but insignificant in multivariate analysis (P = 0.064).During the past decade, coronary computed tomography angiography (coronary CTA) has been accepted as a highly reliable and less invasive modality for CAD diagnosis owing to its high spatial and temporal resolution and excellent diagnostic accuracy [1][2][3][4][5] . Coronary CTA allows the visualization of coronary artery anatomy and the associated atherosclerotic plaques 6-8 . This is represented in the ability of coronary CTA to identify the coronary anatomy as well as the location, distribution, characteristics and composition of plaques in the coronary arteries 6,7,9 .The evaluation of the left main coronary bifurcation angle (LCBA) has gained increasing clinical concern and research interest because the angulation of the LCBA has been shown to have a hemodynamic effect on shear stress, flow turbulence formation and the consequent development of plaques at the bifurcating regions; thus, measurements of the bifurcation angles will provide an insight into demonstrating the relationship among the plaques, CAD and coronary angles 4-6, 8, 10-17 . In previous studies, a wider bifurcation angle has been hypothesized as related to higher turbulence and low shear stress, which might induce plaque proliferation at the bifurcated regions, whereas a narrow angle might be more prone to present laminar flow and less likely to induce plaque formation 4-6, 8, 10-18 . Despite the evidence of a direct correlation between the LCBA and the formation of plaques 4 , to the best of the authors' knowledge, this is the first study to investigate the correlation between the LCBA