We provide a database of the coseismic geological surface effects following the Mw 6.5 Norcia earthquake that hit central Italy on 30 October 2016. This was one of the strongest seismic events to occur in Europe in the past thirty years, causing complex surface ruptures over an area of >400 km2. The database originated from the collaboration of several European teams (Open EMERGEO Working Group; about 130 researchers) coordinated by the Istituto Nazionale di Geofisica e Vulcanologia. The observations were collected by performing detailed field surveys in the epicentral region in order to describe the geometry and kinematics of surface faulting, and subsequently of landslides and other secondary coseismic effects. The resulting database consists of homogeneous georeferenced records identifying 7323 observation points, each of which contains 18 numeric and string fields of relevant information. This database will impact future earthquake studies focused on modelling of the seismic processes in active extensional settings, updating probabilistic estimates of slip distribution, and assessing the hazard of surface faulting.

Understanding the transformations of the climate system may help to predict and reduce the effects of global climate change. The geological record provides a unique archive that documents the long-term fluctuations of environmental variables, such as seasonal change. Here, we investigate how seasonal variation in seawater temperatures varied in the Mediterranean Sea during the early Pleistocene, approaching the Early-Middle Pleistocene Transition (EMPT) and the beginning of precession-driven Quaternary-style glacial-interglacial cycles. We performed whole-shell and sclerochemical stable isotope analyses (δ 18 O, δ 13 C) on bivalves, collected from

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Purpose At the northern fringe of the Po Plain (northern\ud Italy), several isolated hills exist, corresponding to the top of Late Quaternary anticlines. These hills were thoroughly surveyed for their soils and surficial geology, furnishing detailed archives of the palaeoenvironmental evolution of the area. A new, thick and complex loess-paleosol sequence, resting upon fluvial/fluvioglacial deposits, exposed in a quarry at the top of the Monte Netto hill was studied in detail to elucidate its significance.\ud Materials and methods Highly deformed fluvial and\ud fluvioglacial deposits, probably of Middle Pleistocene age,\ud are exposed in a clay pit at Monte Netto, underneath a 2- to\ud 4-m-thick loess-paleosol sequence. A geopedological, sedimentological and micropedological investigation of the sequence shows a distinctive difference between the B horizons forming the sequence, while luminescence and radiocarbon age determinations and the occurrence of Palaeolithic lithic assemblages elucidate the chronology of the sequence.\ud Results and discussion The pedosedimentary sequence consists of several loess layers showing different degrees of\ud alteration; loess deposition and weathering occurred,\ud according to optically stimulated luminescence (OSL) and\ud AMS-14C dating as well as archaeological materials, during\ud the Upper Pleistocene. The lower part of the section consists\ud of strongly weathered colluvial sediments overlying fluvial\ud and fluvioglacial sediments. A tentative model of the exposed profiles involves the burial of the anticline, which forms the core of the hill, by loess strata since Marine Isotopic Stage (MIS) 4 and their subsequent weathering (and truncation) during subsequent interstadials. The degree of weathering of buried B horizons increases from the top of the sequence toward the bottom, suggesting a progressive decrease in the\ud intensity of pedogenesis. Finally, the highly rubified paleosol\ud at the top of the hill is regarded as a buried polygenetic soil or a vetusol, developed near the surface since the Middle\ud Pleistocene.\ud Conclusions The palaeopedological, geochronological and\ud geoarchaeological analyses permit to define the phases and\ud steps of development of the Monte Netto pedosedimentary\ud sequence; the lower part of the sequence is dated to the Mid-Pleistocene, whereas loess accumulation occurred between MIS 4 and MIS 2. Moreover, analyses help to clarify the climatic and environmental context of alternating glacial and interstadial phases, during which the sediments where deposited, deformed and weathered

Little is known regarding coronavirus disease 2019 (COVID-19) clinical spectrum in non-Asian populations. We herein describe the impact of COVID-19 on liver function in 100 COVID-19 consecutive patients (median age 70 years, range 25–97; 79 males) who were admitted to our internal medicine unit in March 2020. We retrospectively assessed liver function tests, taking into account demographic characteristics and clinical outcome. A patient was considered as having liver injury when alanine aminotransferase (ALT) was > 50 mU/ml, gamma-glutamyl transpeptidase (GGT) > 50 mU/ml, or total bilirubin > 1.1 mg/dl. Spearman correlation coefficient for laboratory data and bivariable analysis for mortality and/or need for intensive care were assessed. A minority of patients (18.6%) were obese, and most patients were non- or moderate-drinkers (88.5%). Liver function tests were altered in 62.4% of patients, and improved during follow-up. None of the seven patients with known chronic liver disease had liver decompensation. Only one patient developed acute liver failure. In patients with altered liver function tests, PaO2/FiO2 < 200 was associated with greater mortality and need for intensive care (HR 2.34, 95% CI 1.07–5.11, p = 0.033). To conclude, a high prevalence of altered liver function tests was noticed in Italian patients with COVID-19, and this was associated with worse outcomes when developing severe acute respiratory distress syndrome.