No abstract

As survival rates improve for pediatric cancers, increased attention has been paid to late effects of cancer therapy, in particular, infertility. Fertility preservation options are available for pre- and post-pubertal cancer patients; however, many providers lack knowledge regarding options. The aim of this document is to provide a comprehensive synthesis of current evidence and recommendations regarding fertility preservation options for children, adolescent, and young adults undergoing cancer treatment. A systematic search was performed to identify fertility preservation evidence. Fifty-three studies and four clinical guidelines were used for the review. Final recommendations consisted of two strong and one weak recommendation for both female and male fertility preservation options. The treatment team should be knowledgeable about fertility preservation so that they can educate patients and families about available fertility preservation options. It is important to consider and discuss all available fertility options with patients at the time of diagnosis.