No previous studies have explored the effects of mind–body approaches on health-related quality of life (HRQoL) in the frail elderly. Cognition and action are an inseparable whole during functioning. Thus, a new intervention-based approach using familiarity-based movements and a nonjudgmental approach of “cognition-action” was proposed and was tested with Tai Chi on HRQoL in frail institutionalized elderly. Fifty-two participants (58% women) age 65–94 took part in a 24-wk Tai Chi (TC) intervention 4 days/wk or a cognition-action (CA) exercise program of 30 min twice a week. Changes in Mini Mental State score, physical (PCS) and mental component (MCS) summaries (SF12); Falls Efficacy Scale (FES); and exercise self-efficacy were explored. PCS improved from 33.6 ± 6.7 to 51 ± 4.8 in the TC group and from 30.6 ± 9.9 to 45.1 ± 10.2 in the CA group (p < .001). MCS of SF-12 (p < .001), FES (p < .001), and exercise self-efficacy (p < .01) were enhanced significantly in both groups. Adapted CA programs and Tai Chi were both efficient in improving HRQoL of frail elderly.

The syndrome taxonomies are consistent with the diagnostic criteria. The clinical use of syndrome co-occurrence could help to further understand and evaluate behavioral changes in pharmacological and non-pharmacological treatments.

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