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Sn‐based composites are considered as one of the promising anode materials for sodium‐ion batteries (SIBs) due to their high theoretical capacities and suitable operation voltages. However, they suffer the huge volume change and unstable electrolyte/electrode interface during sodiation/desodiation, which causes structure collapse and serious capacity loss. In the past few years, great efforts have been made to ameliorate the performances of Sn by rationally designing electrode structures/components or optimizing electrolyte composition. Here, the underlying sodium‐storage reactions in Sn are summarized based on the results from theoretical calculations and advanced characterizations. Then, the recent progresses of Sn‐based composites, i.e., Sn‐based alloys, Sn/C composites, and Sn oxides/sulfides, with various structures for SIBs are discussed in details. After that, how the electrolyte affects solid‐electrolyte interphase and the electrochemical performances is shown. Finally, the future directions for the applications of Sn‐based composites in SIBs are suggested. Hence, this review provides a comprehensive scenario about the applications of Sn‐based composites in SIBs. It will benefit the future development of alloy‐type anodes in SIBs.

Ex-situ and in-situ neutron diffraction experiments were performed at HRFD time-of-flight (TOF) diffractometer (IBR-2 long-pulsed reactor, JINR) to characterize the entire battery system based on LiFePO4 and V-added LiFePO4 electrodes during electrochemical cycling and to find additional information about crystal structure of electrodes. Another purpose of this work was checking possibilities for in-situ experiments with real Li-ion batteries at the IBR-2 pulsed reactor. An important advantage of TOF method is the possibility to work at the fixed geometry of the experiment, which allows selecting the optimal battery orientation relative to the directions of the incident and scattered neutron beams and, thus, to minimize the difficulties associated with complex internal structure of the battery. It was shown that charge/discharge process of Li-based real Li-ion battery can be effectively studied by TOF technique at the IBR-2 pulsed reactor. Three full charge/discharge cycles were realized at room temperature (~170C) with slow rate. The step-like appearance of several LiCn phases was observed and the volume fractions of LiFePO4 and FePO4 structural phases at different states of charge were determined. The analysis of changes in cathode material microstructure when doped with vanadium showed a significant increase in the density of defects, which correlates with better electrochemical properties of V-added LiFePO4 compared to pure LiFePO4.

PurposeLung squamous cell carcinoma (LUSC) is a common type of non-small-cell lung cancer. Because of the limitations of targeted therapy and immunotherapy, LUSC treatments are ineffective. To better understand the underlying mechanisms of LUSC carcinogenesis, the present study aimed to identify novel factors and their signaling networks in LUSC, with a primary focus on the construction of a competing endogenous RNA (ceRNA) regulatory network. MethodsWe conducted a transcriptomic analysis of LUSC samples from The Cancer Genome Altas database. Furthermore, we analyzed the data using bioinformatics methods.Results533 samples were selected for analysis, including 485 “PrimaryTumor” samples and 48 “SolidTissueNormal” samples. A total of 1853 DEgenes were identified. Bioinformatics analyses identified the most physiologically relevant and significantly dysregulated lncRNAs and mRNAs. MAGI2-AS3 and ZEB2 were found to play key roles in LUSC. Furthermore, we mapped these signaling pathway based on its role as a miRNA sponge to predict the binding of miRNA to MAGI2-AS3 and ZEB2.ConclusionWe concluded that MAGI2-AS3/ZEB2 loop exhibited tumor-suppressor activity in LUSC by inhibiting miR-374a-5p and miR-374b-5p and modulating the downstream signal transduction through a ceRNA network.