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Background
Should all out‐of‐hospital cardiac arrest (
OHCA
) patients be directly transported to cardiac arrest centers (
CAC
s) remains under debate. Our study evaluated the impacts of different transport time and destination hospital on the outcomes of
OHCA
patients.
Methods and Results
Data were collected from 6655
OHCA
patients recorded in the regional prospective
OHCA
registry database of Taoyuan City, Taiwan, between January 2012 and December 2016. Patients were matched on propensity score, which left 5156 patients, 2578 each in the
CAC
and non‐
CAC
groups. Transport time was dichotomized into <8 and ≥8 minutes. The relations between the transport time to
CAC
s and good neurological outcome at discharge and survival to discharge were investigated. Of the 5156 patients, 4215 (81.7%) presented with nonshockable rhythms and 941 (18.3%) presented with shockable rhythms. Regardless of transport time, transportation to a
CAC
increased the likelihoods of survival to discharge (<8 minutes: adjusted odds ratio [aOR], 1.95; 95%
CI,
1.11–3.41; ≥8 minutes: aOR, 1.92; 95%
CI,
1.25–2.94) and good neurological outcome at discharge (<8 minutes: aOR, 2.70; 95%
CI,
1.40–5.22; ≥8 minutes: aOR, 2.20; 95%
CI,
1.29–3.75) in
OHCA
patients with shockable rhythms but not in patients with nonshockable rhythms.
Conclusions
OHCA
patients with shockable rhythms transported to
CAC
s demonstrated higher probabilities of survival to discharge and a good neurological outcome at discharge. Direct ambulance delivery to
CAC
s should thus be considered, particularly when
OHCA
patients present with shockable rhythms.
Nonsteroidal anti-inflammatory drugs use during ARI episodes, especially parenteral NSAIDs use, was associated with a further increased risk of stroke.
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