To evaluate the burden of air pollution on years of life lost (YLL) in addition to mortality, we conducted a time series analysis based on the data on air pollution, meteorological conditions and 163,704 non-accidental deaths of Ningbo, China, 2009–2013. The mean concentrations of particulate matter with aerodynamic diameter <10 μm, particulate matter with aerodynamic diameter <2.5 μm, sulfur dioxide and nitrogen dioxide were 84.0 μg/m3, 60.1 μg/m3, 25.1 μg/m3 and 41.7 μg/m3, respectively. An increase of 10-μg/m3 in particulate matter with aerodynamic diameter <10 μm, particulate matter with aerodynamic diameter <2.5 μm, sulfur dioxide and nitrogen dioxide was associated with 4.27 (95% confidence interval [CI] 1.17–7.38), 2.97 (95% CI −2.01–7.95), 29.98 (95% CI 19.21–40.76) and 16.58 (95% CI 8.19–24.97) YLL, respectively, and 0.53% (95% CI 0.29–0.76%), 0.57% (95% CI 0.20–0.95%), 2.89% (95% CI 2.04–3.76%), and 1.65% (95% CI 1.01–2.30%) increase of daily death counts, respectively. The impact of air pollution lasted for four days (lag 0–3), and were more significant in the elderly than in the young population for both outcomes. These findings clarify the burden of air pollution on YLL and highlight the importance and urgency of air pollution control in China.
To evaluate the burden of air pollution on years of life lost (YLL) in addition to mortality, we conducted a time series analysis based on the data on air pollution, meteorological conditions and 163,704 non-accidental deaths of Ningbo, China, 2009-2013. The mean concentrations of particulate matter with aerodynamic diameter <10 μm, particulate matter with aerodynamic diameter <2.5 μm, sulfur dioxide and nitrogen dioxide were 84.0 μg/m 3 , 60.1 μg/m 3 , 25.1 μg/m 3 and 41.7 μg/m 3 , respectively. An increase of 10-μg/m 3 in particulate matter with aerodynamic diameter <10 μm, particulate matter with aerodynamic diameter <2.5 μm, sulfur dioxide and nitrogen dioxide was associated with 4.27 (95% confidence interval [CI] 1.17-7.38), 2.97 (95% CI −2.01-7.95), 29.98 (95% CI 19.21-40.76) and 16.58 (95% CI 8.19-24.97) YLL, respectively, and 0.53% (95% CI 0.29-0.76%), 0.57% (95% CI 0.20-0.95%), 2.89% (95% CI 2.04-3.76%), and 1.65% (95% CI 1.01-2.30%) increase of daily death counts, respectively. The impact of air pollution lasted for four days (lag 0-3), and were more significant in the elderly than in the young population for both outcomes. These findings clarify the burden of air pollution on YLL and highlight the importance and urgency of air pollution control in China. Along with its rapid economic growth and the accompanying urbanization and industrialization in the past decades, China is faced with the problem of serious ambient air pollution caused by increasing consumption of coal, power plant emissions, vehicle exhaust and dust from construction sites 1. The adverse impact of air pollution on health has become a great public concern. Air pollution is a complex, heterogeneous mixture of gaseous pollutants and particulate matter (PM) that may vary in composition with geographical areas and meteorological conditions 2. The gaseous compounds causing air pollution mainly include sulfur dioxide (SO 2), nitrogen oxides, ozone, and carbon monoxide 2,3. PM is usually defined according to its aerodynamic diameter, and the PM with an aerodynamic diameter < 10 μm (PM 10) is of great concern, because such pollutants, once inhaled, could ultimately enter the lungs of human and cause serious problems of lungs and heart 2,3. PM 10 is further divided into coarse (2.5 to 10 μm; PM 2.5-10), fine (< 2.5 μm; PM 2.5), and ultrafine (< 0.1 μm; PM 0.1) particles, with smaller particles generally being more deadly in terms of their health effects. Currently, PM 10 , SO 2 and nitrogen dioxide (NO 2) are the principal air pollutants in China 4 , and PM 2.5 has become a hot topic due to the heavy smog frequently seen in many large cities such as Beijing. A large body of evidence has linked air pollution with excess morbidity and mortality 2,5-12. The majority of previous studies that examined the impact of air pollution on excess mortality used daily death counts as dependent variable in their regression analyses. This approach focuses on number of deaths and ignores the difference in ages of deaths, implicitly giving equal weights to the ...
Background: Dementia is a large and growing health problem, and since the majority of dementia patients live at home, caring responsibilities generally fall to family members. Caregivers are often inadequately supported by formal health services and have poorer psychological and physical health. Our study aimed to compare the contributions of publications from different countries, institutions and authors and present a bibliometric analysis to determine the future hotspots and trends in research on the health of and interventions for family dementia caregivers. Methods: Studies published during 1988-2018 were extracted from the Science Citation Index Expanded of the Web of Science. Each publication was evaluated to obtain the basic information. Bibliometric analysis was used to evaluate the number or cooperation networks of publications, countries, institutions, journals, citations, authors, references, and keywords. The resulting articles were analyzed descriptively, and data were produced for VOSviewer. Results: Five hundred forty-two articles were identified.The annual number of relevant publications has increased steadily since approximately 2006. The USA has the highest number of publications (36.2%), followed by the UK (12.9%). China entered late, but research there has developed rapidly. The most productive institution, journal, and author in this field are University College London, the Journal of the American Geriatrics Society, and Orrell M from the UK, respectively. A co-occurrence analysis of keywords reveals a mainstream research focus on burden, depression, quality of life, and corresponding interventions for dementia patient caregivers. The keywords “psychosocial intervention”, “long-term”, “e-learning/online”, “communication”, and “qualitative research” reflect the latest hotspots, appearing in approximately 2017-2018. Conclusion: Our study details the performance statistics of and the main topics and trends in the research on the health of and interventions for dementia caregivers from 1988 to 2018 and provides a comprehensive analysis.
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