In recent years, researches are concentrating on the effectiveness of Transfer Learning (TL) and Ensemble Learning (EL) techniques in cervical histopathology image analysis. However, there have been very few investigations that have described the stages of differentiation of cervical histopathological images. Therefore, in this article, we propose an Ensembled Transfer Learning (ETL) framework to classify well, moderate and poorly differentiated cervical histopathological images. First of all, we have developed Inception-V3, Xception, VGG-16, and Resnet-50 based TL structures. Then, to enhance the classification performance, a weighted voting based EL strategy is introduced. After that, to evaluate the proposed algorithm, a dataset consisting of 307 images, stained by three immunohistochemistry methods (AQP, HIF, and VEGF) is considered. In the experiment, we obtain the highest overall accuracy of 97.03% and 98.61% on AQP staining images and poor differentiation of VEGF staining images, individually. Finally, an additional experiment for classifying the benign cells from the malignant ones is carried out on the Herlev dataset and obtains an overall accuracy of 98.37%.

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Microorganisms are widely distributed in the human daily living environment. They play an essential role in environmental pollution control, disease prevention and treatment, and food and drug production. The analysis of microorganisms is essential for making full use of different microorganisms. The conventional analysis methods are laborious and timeconsuming. Therefore, the automatic image analysis based on artificial neural networks is introduced to optimize it. However, the automatic microorganism image analysis faces many challenges, such as the requirement of a robust algorithm caused by various application occasions, insignificant features and easy under-segmentation caused by the image characteristic, and various analysis tasks. Therefore, we conduct this review to comprehensively discuss the characteristics of microorganism image analysis based on artificial neural networks. In this review, the background and motivation are introduced first. Then, the development of artificial neural networks and representative networks are presented. After that, the papers related to microorganism image analysis based on classical and deep neural networks are reviewed from the perspectives of different tasks. In the end, the methodology analysis and potential direction are discussed.

Microorganisms play a vital role in human life. Therefore, microorganism detection is of great significance to human beings. However, the traditional manual microscopic detection methods have the disadvantages of long detection cycle, low detection accuracy in large orders, and great difficulty in detecting uncommon microorganisms. Therefore, it is meaningful to apply computer image analysis technology to the field of microorganism detection. Computer image analysis can realize high-precision and high-efficiency detection of microorganisms. In this review, first,we analyse the existing microorganism detection methods in chronological order, from traditional image processing and traditional machine learning to deep learning methods. Then, we analyze and summarize these existing methods and introduce some potential methods, including visual transformers. In the end, the future development direction and challenges of microorganism detection are discussed. In general, we have summarized 142 related technical papers from 1985 to the present. This review will help researchers have a more comprehensive understanding of the development process, research status, and future trends in the field of microorganism detection and provide a reference for researchers in other fields.