ABSTRACT: Objective: To determine the role of amiodarone prophylaxis in the prevention of dysrhythmias following coronary artery bypass grafting (CABG) in patients with low ejection fraction (EF). Methods: In this prospective comparative study, we included150 patients who underwent coronary artery bypass grafting (CABG) in Multan Institute of Cardiology within a duration of 07 months from Jan-2019 to Aug-2019 having low ejection fraction (EF ≤35%). In the intervention(amiodarone) group (N=75), 3 mg/Kg of amiodarone was given after removal of X-clamp and before weaning from cardiopulmonary bypass. while in the remaining 75 patients no anti-arrhythmic treatment was given in the peri-operative period. Occurrence of postoperative arrhythmia (AF and bradycardia) during the primary hospital stay after surgery was a primary study endpoint. Results: There was no significant difference between the mean age, gender and body mass index (BMI) of patients in the two groups. Regarding per-operative data, there was no significant difference in number of grafts in amiodarone group 3.9±0.53 and control group 3.04±0.50 (p-value 0.20). Frequency of Atrial fibrillation (AF) after the surgery was significantly differenced in both groups. In the amiodarone group, 13 (17.3%) patients developed POAF and in the control group, POAF occurred in 25 (33.3%) patients (p-value 0.024). Conclusion: Amiodarone prophylaxis significantly lower the incidence of POAF after CABG in patients with low EF. Amiodarone is easy to administer and is a valuable adjuvant for prevention of POAF.
Objective: To review the cases of placenta previa with its optimal outcome, presented at Combined Military Hospital Lahore. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology, Combined Military Hospital, Lahore Pakistan, from Jul 2018 to Jun 2019. Methodology: Total forty-six women, with singleton pregnancy and cephalic presentation were included. Women with placental abruption, having some local cause of antepartum haemorrhage, bleeding disorders, with severe medical disorder were excluded. Doppler ultrasound and MRI pelvis were performed to confirm the placenta previa and morbid adhered placenta (MAP). Results: Mean age of patients was 31.6 ± 3.5 years. Risk factors like previous scar and curettage was observed in 41 (89.1%) and 15(32.6%) patients respectively. On antenatal examination, placenta previa was diagnosed in 38 patients. Obstetrical hysterectomy was performed in 30 (65.2%) cases whereas lower segment caesarean was performed in 16 (34.7%) cases. Conclusion: Placenta previa is leading cause of maternal morbidity and mortality. Tremendous increase in the cesarean section rate is responsible for increased frequency of abnormally implanted placenta and such cases should be managed at tertiary care hospital to get optimal outcome.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.