The proposed work is aimed to investigate the ultraviolet (UV) light absorption capacity and sun protection factor (SPF) of selected plant extracts. Chemical agents are protecting against UV radiations but long exposure may cause allergies to the skin. The alternative is required to overcome such skin allergies, hyperpigmentation, sunburn, photoaging, and skin irritation. The plant products and their phytochemicals have recently been used for their antioxidant property, which can be used for UV absorbance ability and photoprotective property. The methanol extracts of flowers of Butea monosperma, leaves of Neolamarckia cadamba, peel of Punica granatum and leaves of Cymbopogon citratus were prepared by continuous Soxhlet extraction method and their UV absorbance was measured between 200 and 400 nm using UV spectrophotometer at 30µg/ml concentration. Further extracts were subjected to in vitro SPF determination at 20-40 µg/ml concentration by using the Mansur equation between 290 and 320 nm range using a spectrophotometer. All extracts showed UV absorbance capacity in 200-400 nm range and the P. granatum extracts having higher SPF. The SPF for B. monosperma flowers, N. cadamba leaves, P. granatum, and C. citratus leaves were found to be 2.1430 ± 0.0271, 2.2892 ± 0.0287, 4.1401 ± 0.0551, 0.8751 ± 0.0112 at 20 µg/ml, 2.3824 ± 0.0301, 2.3020 ± 0.0284, 4.3373 ± 0.0566, and 1.0940 ± 0.0140 at 30µg/ml and 2.5953 ± 0.0328, 2.7789 ± 0.0345, 6.0643 ± 0.0804, and 1.8765 ± 0.0239 at 40 µg/ml, respectively. The initial study proved the UV absorbing and Sun protecting capacity of selected plant extracts. This finding suggests that the extracts can be considered to develop photoprotective formulation in different combinations and proportions, which will provide an additive or synergetic effect. The proposed spectrophotometric method is simple, convenient and cost-effective for SPF determination.
The data existing in this article are associated to the antidiabetic activity of ethyl acetate extract of Putranjiva roxburghii Wall barks (EAPR) in streptozotocin (STZ) induced diabetic rats at a dose of 250 & 500 mg/kg by oral route for 21 days. The phytochemical screening of the extract was carried out by gas chromatography and mass spectrometry. Diabetes was induced by streptozotocin (50 mg/kg; i.p), EAPR (250 & 500 mg/kg; b.wt) and standard Insulin (6 IU/animal; subcutaneous; o.i.d) were administered to the diabetic rats. Body weight and blood glucose were estimated weekly. Cholesterol, SOD and CAT were estimated in the blood serum on 21 days of the investigation period. Oral administration of EAPR (500 mg/kg) significant rises in the body weight, decrease in the blood glucose and total cholesterol and restore function of SOD and CAT enzymes (P < 0.05). Current data were also supported by histological study, necrosis was observed in the diabetic rat pancreas; however, necrosis was less observable in treated groups. These findings reveal that an ethyl acetate extract of Putranjiva roxburghii Wall barks shows antihyperglycemic, anti-cholesterolemic, antioxidant and improved the cell density of β-cells of islets of Langerhans in diabetic rats.
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